Results 81 to 90 of about 140,290 (285)

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Comprehensive Review of SDN Controller Placement Strategies

IEEE Access, 2020
Software-Defined Networking (SDN) is a network paradigm introduced to overcome the inherent challenges of traditional networks. Its architecture is either deployed with a single controller or multiple controllers.
Bassey Isong, Reorapetse Ramoliti Samuel Molose, Adnan M. Abu-Mahfouz, Nosipho Dladlu   +3 more
doaj   +1 more source

Backhaul-Aware Caching Placement for Wireless Networks

, 2015
As the capacity demand of mobile applications keeps increasing, the backhaul network is becoming a bottleneck to support high quality of experience (QoE) in next-generation wireless networks. Content caching at base stations (BSs) is a promising approach
Letaief, Khaled B., Peng, Xi, Shen, Juei-Chin, Zhang, Jun   +3 more
core   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Construction of AC Motor Controllers for NOvA Experiment Upgrades

, 2011
I have been constructing Alternating Current (AC) motor controllers for manipulation of particle beam detectors. The capability and reliability of these motor controllers are essential to the Laboratory's mission of accurate analysis of the particle beam'
,, /Fermilab, Cooley, Patrick
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Securing SDN controller placement with MuZero and blockchain-based smart contracts

Journal of King Saud University: Computer and Information Sciences
Software-Defined Networking (SDN) has revolutionized network administration with its unparalleled flexibility and programmability. The secure placement of controllers within a Software-Defined Networking framework remains a significant challenge.
Ouafae Benoudifa, Abderrahim Ait Wakrime, Redouane Benaini   +2 more
doaj   +1 more source