Results 181 to 190 of about 1,550,042 (267)

Impact of Metabolic Syndrome on Patient-Reported and Clinical Outcomes in Patients Undergoing Primary Total Joint Arthroplasty. [PDF]

J Am Acad Orthop Surg Glob Res Rev
Johnson AH, Brennan JC, Parker J, MacDonald JH, King PJ, Turcotte JJ.   +5 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Prevalence of malnutrition and its prognostic impact in lung metastasis patients treated with SBRT: insights from NRI, CONUT, NRS, and PNI. [PDF]

Front Nutr
Zhang Y, Shan J, Gu B, Huang R, Liu H.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The second messenger c-di-AMP controls natural competence via ComFB signaling protein

Cell Discovery
Sherihan Samir, Sofía Doello, Andreas M. Enkerlin, Erik Zimmer, Michael Haffner, Teresa Müller, Lisa Dengler, Stilianos P. Lambidis, Shamphavi Sivabalasarma, Sonja-Verena Albers, Khaled A. Selim   +10 more
doaj   +1 more source

The prognostic role of prognostic nutritional score, geriatric nutritional risk index, and controlling nutritional status score in critically ischemic geriatric patients with acute ischemic stroke: A retrospective cohort study. [PDF]

Medicine (Baltimore)
Arslan K, Arslan HC, Sultan Sahin A.
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Mind the size: LARGE3-OsHDT1 complex keeps rice grain size in line. [PDF]

Plant Cell
Pereyra-Bistraín LI.
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Symptom severity, neighborhood crime, and neural correlates of reappraisal in patients with major depression and social anxiety. [PDF]

Psychol Med
Feurer C, Jimmy J, Uribe M, Burkhouse KL, Shankman SA, Phan KL, Ajilore O, Klumpp H.   +7 more
europepmc   +1 more source