Results 191 to 200 of about 1,550,042 (267)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Correction: Controlling recurrent scabies outbreaks in a geriatric hospital: impact of a prevention bundle and lessons from a breakthrough case. [PDF]

Front Public Health
Li L, Li R, Wang Y, Qian K.
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Editorial: Immune functions of neuroglia. [PDF]

Front Immunol
Pfeiffer F, Verkhratsky A, Garaschuk O.
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Comment on: Metabolic comorbidities and post-transplant outcomes in Metabolic dysfunction-Associated Steatotic Liver Disease (MASLD): a cohort study from a Brazilian tertiary center. [PDF]

Arch Endocrinol Metab
Mumtaz Z, Talpur S, Talpur H.
europepmc   +1 more source

The Effect of Rate-Controlling Medication on the Performance and Outcome of Dobutamine Stress Echocardiography in the Assessment of Patients with Suspected Angina: A Retrospective Cohort Study. [PDF]

J Clin Med
Hariharan L, Amjad MZ, John ET, Cospite V, Chattopadhyay S, Kardos A.   +5 more
europepmc   +1 more source

Eating attitudes and trauma in third-generation holocaust survivors. [PDF]

Front Psychol
Biran G, Jakob L.
europepmc   +1 more source

LpxC activity regulation: An emerging paradigm for controlling lipopolysaccharide synthesis. [PDF]

Trends Microbiol
Nathawat R, Liu C, Mi W.
europepmc   +1 more source