Results 101 to 110 of about 348,009 (316)

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni   +19 more
wiley   +1 more source

Anti‐CD19 CAR T Cells in Autoimmune Encephalitis: Inflammation Controlled, Neurodegeneration Unchecked?

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Just recently, successful chimeric antigen receptor (CAR) T cell therapy was reported in the first patient with refractory, anti‐diacylglycerol lipase alpha (DAGLA) antibody‐mediated autoimmune encephalitis, achieving partial clinical remission.
Dimitrios Mougiakakos   +9 more
wiley   +1 more source

Controversy -Should we give thrombolysis to patients with submassive pulmonary embolism?

open access: yes, 2015
European Congres of the European Society of Emergency Medicine (EUSEM), oct 2015, Torino, Italie. Orateur: “-Controversy -Should we give thrombolysis to patients with submassive pulmonary embolism?
Verschuren, Franck   +1 more
core  

What was the Investiture Controversy a controversy about? [PDF]

open access: yes, 2005
The Investiture Controversy between Pope Gregory VII and Emperor Henry IV of Germany presents us with a wide variety of issues that are not immediately discernable at first sight.
Knight, Emma
core  

Cooperative Learning, Responsibility, Ambiguity, Controversy and Support in Motivating Students

open access: yes, 2007
This paper argues that student motivation is nurtured more by intrinsic rather than extrinsic rewards. Rather than relying on grades alone to stimulate students, this paper explores how engendering a natural critical learning environment can give ...
Jacy Jensen, Ronald Brecke, PhD
core   +1 more source

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou   +16 more
wiley   +1 more source

Sleeping Beauty in Quantumland [PDF]

open access: yes, 2001
It is argued that thirder resolution of the Lewis - Elga controversy about Sleeping Beauty is more clear when the coin toss is replaced by a quantum measurement and the analysis is performed in the framework of the Many-Worlds ...
Vaidman, Lev
core  

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro   +6 more
wiley   +1 more source

Impact of Plasma p‐tau181 on Cognition, Motor Phenotypes, and Disease Course in ALS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Phosphorylated tau181 (p‐tau181), an Alzheimer's disease biomarker, was recently evaluated in amyotrophic lateral sclerosis (ALS). We investigated plasma p‐tau181 in 202 ALS/ALS‐FTD patients and 94 healthy controls, assessing cognitive performance, motor function, and longitudinal dynamics.
Elisabeth Kasper   +25 more
wiley   +1 more source

Controversy Spaces A model of scientific and philosophical change

open access: yes
The notion of controversy space is the key element of the new model of scientific and philosophical change introduced in this book. Devised as an alternative to classical models, the model of Controversy Spaces is a heuristic tool for the reconstruction ...
Nudler, Oscar.
core  

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