Results 171 to 180 of about 19,071 (296)

Focal therapy using a novel cooled laser device for prostate cancer: early trial results

BJU International, EarlyView.
Objectives To determine the short‐term oncological results and safety of the ProFocal Laser Therapy for Prostate Tissue Ablation (PFLT‐PC) trial, the first phase II clinical trial of ProFocal® (Medlogical Innovations, Sydney, Australia), a novel, cooled laser focal therapy (cLFT) device for prostate cancer (PCa) treatment. Patients and Methods Men with
Jonathan Kam, Bishoy Hanna, Stuart Jackson, Stephen McCombie, George McClintock, Matthew J. Roberts, Jake Rahkala, Jeremy Teoh, Mohan Arianayagam, Bertram Canagasingham, Ahmed Saeed Goolam, Nicola Jeffery, Matthew Winter, Mohamed Khadra, Raymond Ko, Nicholas Mehan, Isaac Thangasamy, Celi Varol   +17 more
wiley   +1 more source

Moderate and severe traumatic brain injury: lesion frequency distribution maps and prognostic importance of brain contusions on early MRI. [PDF]

Eur Radiol
Eliassen TS, Bø LE, Flusund AH, Köster AK, Andelic N, Skandsen T, Vik A, Moen KG.   +7 more
europepmc   +1 more source

Patient‐derived surgical samples reveal the cellular and molecular signatures of glioblastoma infiltration in distinct radiological zones

Brain Pathology, EarlyView.
Integrated histological and transcriptional profiling of the glioblastoma periphery reveals clinically relevant tumor infiltration beyond MRI‐defined boundaries. MRI‐guided biopsies from contrast‐enhancing (CE), non‐contrast‐enhancing (nCE), edema (E), and radiologically normal (N) regions demonstrate that nCE areas frequently retain neoplastic and ...
Olaya de Dios, Juan Romero, María de los Ángeles Ramírez‐González, Beatriz Herranz, Alicia Avis‐Bodas, Juliana Manosalva, Diego Megías, Ana Ramos, Juan Manuel Sepúlveda‐Sánchez, Ricardo Gargini, Berta Segura‐Collar, Gabriel Velilla, Bárbara Meléndez, Pedro González, Luis Jiménez‐Roldán, Guillermo García‐Posadas, Aurelio Hernández‐Laín, Ángel Pérez‐Núñez, Pilar Sánchez‐Gómez   +18 more
wiley   +1 more source

Post-craniotomy Troponin Elevation Without Ischemia After Traumatic Brain Injury: A Case Report and Management Framework. [PDF]

Cureus
Álvarez Barrientos AG, Carvajal Méndez K, Ulate Fuentes D, Gutiérrez Rivera F, Aragón Leiva D.   +4 more
europepmc   +1 more source

Haemostatic changes and bleeding with anti‐IL‐6 directed therapy in autoimmune diseases

British Journal of Pharmacology, EarlyView.
Abstract Anti‐IL‐6 directed therapy, especially tocilizumab (TCZ), is widely used for the treatment of autoimmune diseases such as rheumatoid arthritis, giant cell arteritis and systemic juvenile idiopathic arthritis. Next to being a master regulator of inflammation, IL‐6 also is an important regulator of haemostasis. Although generally well tolerated,
Charlotte D. C. C. van der Heijden, Loes C. Oskam, Lenny van Bon, Chantal P. Rovers   +3 more
wiley   +1 more source

Impact of Osilodrostat on Health‐Related Quality of Life in Cushing's Disease: Analysis of Patient‐Reported Outcomes From the Phase III LINC 3 and LINC 4 Clinical Trials

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Evaluate the effects of osilodrostat short‐ and long‐term treatment on health‐related quality of life (HRQoL) in Cushing's disease. Design LINC 3 and LINC 4 studies (pooled analysis). Patients 185 patients (mean baseline total scores: Cushing's Quality of Life [CushingQoL], 44.0; Beck Depression Inventory II [BDI‐II], 15.6; EuroQol ...
John Newell‐Price, Beverly M. K. Biller, Maria Fleseriu, Beatrice Gueron, Grzegorz Binowski, Anna Paćkowska, Mônica R. Gadelha   +6 more
wiley   +1 more source

Injury Epidemiology in Elite U17 Football Players: A Prospective Study Across Six Competitive Seasons. [PDF]

Life (Basel)
Pranjić T, Žuvela F, Modrić T, Stojanović M, Bandalović A, Turić A, Barić T, Škomrlj J, Veršić Š.   +8 more
europepmc   +1 more source

Contusion [PDF]

, 2020
openaire   +1 more source

Safety Assessment in Child Protection—A Survey Study With Dutch Child Protection Workers

Child &Family Social Work, EarlyView.
ABSTRACT Safety assessment is a crucial part of child protective services to estimate acute and chronic danger in families that are at risk for child abuse in order to determine whether and which steps need to be taken to protect the child's safety. This study aimed to gain insight into the usefulness of the safety assessment procedure at Dutch child ...
B. Erens, H. Gerger, E. Simon
wiley   +1 more source

<i>Chest In Time</i>: Investigating the utility of a novel X-ray based blunt chest trauma clinical prediction model in a resource-limited setting in South Africa. [PDF]

SA J Radiol
Kalideen A, Sewchuran T.
europepmc   +1 more source