Results 11 to 20 of about 1,778 (188)

Accelerating Subcutaneous Drug Development: A Mechanistic Absorption Model for the Open Systems Pharmacology Framework. [PDF]

CPT Pharmacometrics Syst Pharmacol
ABSTRACT This study describes the implementation of a mechanistic subcutaneous (SC) injection model for the Open Systems Pharmacology platform. As the SC route of administration is gaining increased popularity, there is a growing need for tools to predict, analyze, and understand the SC absorption process and the mechanisms involved.
Pellowe M, Dubbelboer I, Sjögren E.
europepmc   +2 more sources

Comparative Analysis of Convection Permitting Model and Cumulus Parameterization for Simulation of Summer Precipitation over Qinghai-Xizang （Tibetan） Plateau

Gaoyuan qixiang, 2023
The Qinghai-Xizang （Tibetan） Plateau is known as the Asian water tower.The change of its water resources has an important impact on the weather and climate in the lower reaches.Precipitation is a key role in the water cycle.Therefore， it is of great ...
Ying CHEN, Xianyu YANG, Yaqiong LÜ, Jun WEN, Jianing ZHU   +4 more
doaj   +1 more source

A Moist Physics Parameterization Based on Deep Learning

Journal of Advances in Modeling Earth Systems, 2020
Current moist physics parameterization schemes in general circulation models (GCMs) are the main source of biases in simulated precipitation and atmospheric circulation.
Yilun Han, Guang J. Zhang, Xiaomeng Huang, Yong Wang   +3 more
doaj   +1 more source

Basic Concepts for Convection Parameterization in Weather Forecast and Climate Models: COST Action ES0905 Final Report

Atmosphere, 2014
The research network “Basic Concepts for Convection Parameterization in Weather Forecast and Climate Models” was organized with European funding (COST Action ES0905) for the period of 2010–2014.
Jun–Ichi Yano, Jean-François Geleyn, Martin Köhler, Dmitrii Mironov, Johannes Quaas, Pedro M. M. Soares, Vaughan T. J. Phillips, Robert S. Plant, Anna Deluca, Pascal Marquet, Lukrecia Stulic, Zeljka Fuchs   +11 more
doaj   +1 more source

Effects of Organized Convection Parameterization on the MJO and Precipitation in E3SMv1. Part I: Mesoscale Heating

Journal of Advances in Modeling Earth Systems, 2021
Mesoscale organization of convection is typically not represented in global circulation models, and hence its influence on the global circulation is not accounted for. The heating component of a parameterization that represents the dynamical and physical
C.‐C. Chen, J. H. Richter, C. Liu, M. W. Moncrieff, Q. Tang, W. Lin, S. Xie, P. J. Rasch   +7 more
doaj   +1 more source

Impact of Interactive Vertical Overlap of Cumulus and Stratus on Global Aerosol, Precipitation, and Radiation Processes in the Seoul National University Atmosphere Model Version 0 With a Unified Convection Scheme (SAM0‐UNICON)

Journal of Advances in Modeling Earth Systems, 2019
The previously proposed parameterization for the integrated vertical overlap of cumulus and stratus is generalized to handle both conventional exponential‐random stratus overlap and nonconventional (i.e., other than exponential‐random) cumulus overlap in
Sungsu Park, Eunsil Oh, Siyun Kim, Jihoon Shin   +3 more
doaj   +1 more source

Improvement in the Modeled Representation of North American Monsoon Precipitation Using a Modified Kain–Fritsch Convective Parameterization Scheme

Atmosphere, 2018
A commonly noted problem in the simulation of warm season convection in the North American monsoon region has been the inability of atmospheric models at the meso-β scales (10 s to 100 s of kilometers) to simulate organized convection, principally ...
Thang M. Luong, Christopher L. Castro, Truong M. Nguyen, William W. Cassell, Hsin-I Chang   +4 more
doaj   +1 more source

Parameterization of Stochastically Entraining Convection Using Machine Learning Technique

Journal of Advances in Modeling Earth Systems, 2022
A stochastic mixing model with a machine learning technique is proposed for mass flux convection schemes. The model consists of the stochastic differential equations (SDEs) for the fractional entrainment rate, fractional detrainment rate, fractional ...
Jihoon Shin, Jong‐Jin Baik
doaj   +1 more source

Characterizing Convection Schemes Using Their Responses to Imposed Tendency Perturbations

Journal of Advances in Modeling Earth Systems, 2021
Convection is usually parameterized in global climate models, and there are often large discrepancies between results obtained with different convection schemes.
Y. L. Hwong, S. Song, S. C. Sherwood, A. J. Stirling, C. Rio, R. Roehrig, C. L. Daleu, R. S. Plant, D. Fuchs, P. Maher, L. Touzé‐Peiffer   +10 more
doaj   +1 more source

Evaluating a lightning parameterization based on cloud-top height for mesoscale numerical model simulations [PDF]

Geoscientific Model Development, 2013
The Price and Rind lightning parameterization based on cloud-top height is a commonly used method for predicting flash rate in global chemistry models.
J. Wong, M. C. Barth, D. Noone
doaj   +1 more source