Results 101 to 110 of about 2,094,503 (306)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

La construction politique de la commune mesure de la qualité des eaux superficielles en France : de l’équivalent-habitant au bon état (1959-2013)

open access: yesDéveloppement Durable et Territoires, 2017
Public authorities in charge of preparing and implementing the 1964 French water law and the 2000 European Water framework Directive similarly relied on inventories. In order to justify public action, they needed to objectify a situation which was either
Gabrielle Bouleau   +3 more
doaj   +1 more source

The Road to a Constitutional Convention: Reforming the New York State Unified Court System and Expanding Access to Civil Justice [PDF]

open access: yes, 2017
This article will focus on the judiciary reforms and access to justice—starting with reforms to the structure of the Unified Court System and discussing other ways that a constitutional convention might serve to improve the operation of the courts.
Lippman, Jonathan
core   +1 more source

Conventional Mechanical Ventilation

open access: yesSaudi Journal of Anaesthesia, 2010
The provision of mechanical ventilation for the support of infants and children with respiratory failure or insufficiency is one of the most common techniques that are performed in the Pediatric Intensive Care Unit (PICU). Despite its widespread application in the PICUs of the 21st century, before the 1930s, respiratory failure was uniformly fatal due ...
openaire   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The Influence Of Generation Z Participation In Implementing Events In Tabanan District Tourism Villages

open access: yesJourney
Tabanan Regency has 133 villages, 28 of which have become tourist villages in 2023. Several tourist villages hold promotional events through social media. Generation Z uses social media the most, but tourist village managers have not involved Generation
Anak Agung Ketut Sri Candrawati   +2 more
doaj   +1 more source

Are Natural Languages Necessary?

open access: yesCrítica, 2019
Against Davidson's criticism of the usual notion of a natural language, Dummett and most philosophers of language have argued that such a notion is necessary to account for the normativity of meaning and to avoid declaring meaningless much of our ...
Manuel Hernández Iglesias
doaj   +1 more source

The Brussels Convention:a still born child? [PDF]

open access: yes, 1999
Whether status of Brussels Convention as international treaty rather than EU treaty limits its potential and ...
O'Neill, Maria
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Hope vs. Fear: The Debate Over a State Constitutional Convention [PDF]

open access: yes, 2017
On November 7, 2017, New Yorkers will go to their polling places and receive ballots containing a thirteen-word referendum question: “Shall there be a convention to revise the constitution and amend the same?” That question appears on the ballot because ...
Greenberg, Henry M.
core   +1 more source

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