Results 51 to 60 of about 522,574 (291)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The Administration of Another Person’s Assets

open access: yesCECCAR Business Review, 2021
The aim of this article is to present the concept of administration, showing the features of this legal institution, and the types of administration, and to identify the specificity for each administration type and the legal regime for each type of ...
Ioana Nely MILITARU
doaj   +1 more source

Social alliances improve rank and fitness in convention-based societies

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Significance What forces produce and maintain social inequality, and why do society members tolerate this inequality? The “One Percent” clearly benefit from having high status, but low-status individuals have strong incentive to challenge the established
Eli D. Strauss, K. Holekamp
semanticscholar   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

ANALYSE JURIDIQUE DE L’ENCADREMENT INTERÉTATIQUE DU COMMERCE INTERNATIONAL [PDF]

open access: yesCahiers Africains des Droits de l’Homme et de la Démocratie ainsi que du Développement Durable, 2022
Les conventions de droit matériel ont, dans les domaines où elles interviennent, un effet décisif d'unification. Il en résulte que le droit commercial international de la matière devient commun à tous les Etats contractants.
Godefroid-Specter AFILI POKHO
doaj  

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

The Impact of Different Value Types on Environmentally Responsible Behavior: An Empirical Study from Residents of National Park Communities in China

open access: yesLand
The construction of China’s national park system is an important part of the ecological civilization development strategy, and the behavior of the subjects in the national park has a great impact on its sustainable development.
Yechen Zhang   +4 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Minimizing Medication Errors from Electronic Prescription Transmission—Digitizing Compounded Drug Preparations

open access: yesPharmacy, 2019
Lack of standardization related to compounded drug preparations, especially in the transition of care situations, threatens patient safety by facilitating medication error.
Richard H. Parrish   +5 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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