Results 51 to 60 of about 17,419 (258)

Taxonomic bias and international biodiversity conservation research

open access: yesFACETS, 2016
While greater research on threatened species alone cannot ensure their protection, understanding taxonomic bias may be helpful to address knowledge gaps in order to identify research directions and inform policy. Using data for over 10 000 animal species
Michael R. Donaldson   +6 more
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Digitalising biodiversity: Exploring perceptions on risks and opportunities

open access: yesPlants, People, Planet
Societal Impact Statement Digitalisation is transforming biodiversity conservation, offering new opportunities for research, governance and public engagement.
Björn‐Ola Linnér   +9 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Climate Change and Health: Transcending Silos to Find Solutions

open access: yesAnnals of Global Health, 2015
Background: Climate change has myriad implications for the health of humans, our ecosystems, and the ecological processes that sustain them. Projections of rising greenhouse gas emissions suggest increasing direct and indirect burden of infectious and ...
Catherine Machalaba   +6 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Contributions of Citizen Science to the United Nations Sustainable Development Goals and Other International Agreements and Frameworks

open access: yesCitizen Science: Theory and Practice, 2023
Dilek Fraisl   +4 more
doaj   +1 more source

RANCANGAN UNDANG-UNDANG PENGETAHUAN TRADISIONAL DAN EKSPRESI BUDAYA TRADISIONAL DITINJAU DARI ASPEK BENEFITS PASAL 8J UNCBD

open access: yesArena Hukum, 2016
Traditional Knowledge and Traditional Cultural Expressions in Indonesian positive law isset out in the legal system of intellectual property rights , in this case is the Law. 19 of 2002 on Copyright.
Yeni Eta
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

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