Results 61 to 70 of about 408,939 (300)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Ósýnileiki barna sem leita alþjóðlegrar verndar á Íslandi í fylgd foreldra
Nordicum-Mediterraneum, 2019 Invisibility of children of asylum-seeking families in Iceland According to the Convention on the Rights of the Child, asylum-seeking children should be given the same rights as other children in Iceland.
Helga Gudmundsdóttir +2 more
doaj
Convention on the Rights of the Child
Journal of Nepal Paediatric Society, 1970 doi:10.3126/jnps.v29i1.1601J. Nepal Paediatr. Soc.
openaire +2 more sources
This Is Not a Myeloproliferative Neoplasm…
Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Is there a place for work in child development? Implications of child development theory and research for interpretation of the UN Convention on the Rights of the Child, with particular reference to Article 32, on children, work and exploitation [PDF]
, 1999 This paper is about the role of child-development knowledge and research in international efforts to improve the lives and prospects for millions of working children.
Woodhead, Martin
core
Supporting the Transition of Pupils from Primary to Secondary School using the MindJump Health and Well-being Programme [PDF]
, 2016 The United Nations Convention on the Rights of the Child (United Nations, 1989) enshrined the rights of children and young people to participate in decisions affecting their lives.
Hannah, Elizabeth +2 more
core +4 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Safeguarding Children in the Developing World—Beyond Intra-Organisational Policy and Self-Regulation
Social Sciences, 2020 Safeguarding in the context of development and humanitarian assistance has received heightened international attention since 2018. Emerging literature has not yet investigated the extent to which responses are evolving in the best interests of the child,
Afrooz Kaviani Johnson +1 more
doaj +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source