Results 71 to 80 of about 408,939 (300)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Ergenlerin Çocuk Hakları Hakkındaki Görüşlerinin İncelenmesi
Ankara Sağlık Bilimleri Dergisi, 2020 Amaç: “Çocuk Hakları” çocukların doğumdan itibaren sahip oldukları; ırk, dil, din, cinsiyet ya da toplumsal farklılıkları kabul etmeden sahip olunan ve çocukların yüksek yararını korumayı amaçlayan haklardır.
Zehra Eriş, Figen Gürsoy, Nur Sena Öz
doaj
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
The Domestication of the United Nations, Convention on the Rights of the Child in South Africa
African Journal of Political ScienceThe domestication of the United Nations Convention on the Rights of the Child (CRC) in South Africa presents a critical constitutional commitment towards protecting the rights of children.
Raymond Chirowamhangu, Ruth Nyamadzawo
doaj +1 more source
International Laws of War and the African Child: Norms, Compliance, and Sovereignty [PDF]
The Convention on the Rights of the Child of 1989 is one of the most prominent international humanitarian treaty in world history. It entered into force quicker than any other treaty and currently only two countries (the United States and Somalia) have ...
Jeffrey Herbst
core
“Braxton Hick’s” or the birth of a new era? Tracing the development of Ireland’s abortion laws in respect of European Court of Human Rights Jurisprudence [PDF]
, 2011 In Ireland, Article 40.3.3° of Bunreacht na hÉireann (the Irish Constitution) guarantees the right to life of the unborn child and the equal right to life of the mother.
Daly, Brenda
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Children's Convention (Convention on the Rights of the Child)
, 2009 The five-volume Encyclopedia of Human Rights, edited by David Forsythe, offers comprehensive coverage of all aspects of human rights theory, practice, law, and history in over 300 entries signed by leading scholars and human rights experts. The coverage includes major figures, organizations and institutions, human rights events and crises, and human ...
Besson, Samantha +1 more
openaire +2 more sources
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source