Results 71 to 80 of about 409,392 (349)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

The Domestication of the United Nations, Convention on the Rights of the Child in South Africa

African Journal of Political Science
The domestication of the United Nations Convention on the Rights of the Child (CRC) in South Africa presents a critical constitutional commitment towards protecting the rights of children.
Raymond Chirowamhangu, Ruth Nyamadzawo
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Children's Convention (Convention on the Rights of the Child)

, 2009
The five-volume Encyclopedia of Human Rights, edited by David Forsythe, offers comprehensive coverage of all aspects of human rights theory, practice, law, and history in over 300 entries signed by leading scholars and human rights experts. The coverage includes major figures, organizations and institutions, human rights events and crises, and human ...
Besson, Samantha, Bourke-Martignoni, Joanna   +1 more
openaire   +2 more sources

The Non-government Report on the Implementation of the Convention on the Rights of the Child in Australia, Contribution by SCALES authors [PDF]

, 2005
This non-government report to the United Nations Committee on the Rights of the Child responds to the Australian Government’s Combined Second and Third Reports and makes recommendations to further Australia’s compliance with the United Nations Convention
National Children’s and Youth Law Centre and Defence for Childre,
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

International Laws of War and the African Child: Norms, Compliance, and Sovereignty [PDF]

The Convention on the Rights of the Child of 1989 is one of the most prominent international humanitarian treaty in world history. It entered into force quicker than any other treaty and currently only two countries (the United States and Somalia) have ...
Jeffrey Herbst
core  

The Voice Of The Child in International Child Abduction Proceedings Under the 1980 Hague Convention [PDF]

, 2019
With the thirtieth anniversary of the United Nations Convention on the Rights of the Child (hereafter the UNCRC) being celebrated in 2019, this timely project was undertaken to consider the practical application of the right of the child to participate ...
Freeman, M., Taylor, N., and Schuz, R., Freeman, M., Taylor, N., and Schuz, R.   +1 more
core  

Listening and responding? Children's participation in health care within England [PDF]

, 2005
This article examines recent health policy developments in England in relation to children's rights under Article 12 and 13 of the United Nations Convention on the Rights of the Child (UNCRC).
Franklin, Anita, Sloper, Patricia
core   +1 more source