Results 51 to 60 of about 2,176,645 (266)
Effect of organic and conventional farming system and sowing date on yield, seed oil and protein content in rapeseed cultivars [PDF]
Ratarstvo i Povrtarstvo, 2020 Rapeseed is one of the major oil crops, grown in various agroecological conditions. Interest in organic rapeseed is rising, with increasing importance to breeders to determine the need for specific organic breeding programs.
Terzić Sreten +7 more
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FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Journal of Contemporary PharmacyTizanidine Hydrochloride is commonly used to treat multiple sclerosis spastic diplegia, backache, and injuries to central nervous system (CNS). Objective: This study aimed to develop quick-release films of tizanidine HCl to create a dosage form that ...
Sadia Shehzad, Ali Zafar, Abdul Basit
doaj +2 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
THE INFLUENCE OF RAISA TECHNOLOGY APPLICATION ON FARMER’S INCOME IN MUARA TELANG DISTRICT OF BANYUASIN REGENCY, INDONESIA [PDF]
Russian Journal of Agricultural and Socio-Economic Sciences, 2022 The purpose of this research was to analyze the influence of RAISA technology application on Farmer’s Income in Muara Telang District, Banyuasin Regency; This research conducted in Telang Makmur, Telang Rejo and Sumber Hidup Village, Muara Telang ...
Utari N.N.K., Mulyana A., Sari D.W.
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Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
FoodsThis study evaluated the efficacy of ammonia-nitrogen-reducing biofilms (aquatic nitrifying bacteria biofilm media, a fixed-bed biofilm capable of simultaneous nitrification and denitrification) in mitigating water quality deterioration and transport ...
Xianxian Zhang +7 more
doaj +1 more source