Results 61 to 70 of about 668 (250)

Normative talk about talk in child-caregiver interaction in Mexican families

open access: yesPsychology of Language and Communication
This article shares the current interest in characterizing family interaction with children in different communities. I have investigated one aspect of possible diversity that is rarely reported: the normative discourse that caregivers direct towards ...
Rojas-Nieto Cecilia
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Las características psicológicas de los alumnos en la enseñanza integrada

open access: yesEscuela Abierta, 2019
The text is devoted to analysis of mental qualities of: a) children starting their education at primary school, b) children attending the following years at the stage of integrated education.
Stanislaw Nieciunski
doaj   +2 more sources

Europejski Trybunał Praw Człowieka jako europejski sąd konstytucyjny

open access: yesPrzegląd Konstytucyjny
The article presents arguments in favor of defining the European Court of Human Rights as a “European constitutional court,” and from that angle analyzes its approach to the rule of law crisis in ...
Marcin Szwed
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Public Policies and Conventionality Control

open access: yes, 2022
Las políticas públicas son acciones ejecutadas por los Estados para satisfacer situaciones entendidas como problemas públicos. El control de convencionalidad es una obligación estatal, contraída de buena fe al ratificar la Convención Americana de derechos humanos y reconocer la competencia contenciosa de la Corte Interamericana. Ambos temas tienen como
openaire   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

El control de convencionalidad: análisis en derecho comparado

open access: yesRevista Direito GV
En el caso Almonacid (2006), por primera vez, la Corte Interamericana de Derechos Humanos enunció la doctrina del control de convencionalidad.
Gonzalo Aguilar Cavallo
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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