Results 31 to 40 of about 14,183 (250)
Freezing of saccades in dopa-responsive parkinsonian syndrome
American Journal of Ophthalmology Case Reports, 2021 Purpose: Ocular motor abnormalities such as abnormal saccades are common in idiopathic Parkinson's disease (PD) and atypical parkinsonian syndrome, such as progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD).
Techawit Likitgorn +2 more
doaj +1 more source
Ocular effects of acute ingestion of Cola nitida(Linn) on healthy adult volunteers
African Vision and Eye Health, 2007 Cola nitida Linn (Sterculiaceae) is an economic plant widely distributed throughout West Africa and possibly other parts of Africa.Members are malvalves because of their lobular nature.
S. A. Igwe, D. N. Akunyili, E. U. Ikonne
doaj +1 more source
Prevalence of ocular morbidity in school going children in West Uttar Pradesh
Indian Journal of Ophthalmology, 2017 Aim of the Study: This study aims to evaluate the prevalence and to make a comparison between the ocular morbidity pattern in school going children of urban and rural areas of West Uttar Pradesh.
Veer Singh +3 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier +11 more
wiley +1 more source
Ocular motility consequences following lesions of the thalamus: a literature review
British and Irish Orthoptic Journal, 2009 Aim: To summarise the anatomy and function of the thalamus and review the medical literature for types of thalamic lesions and resultant ocular motility deficits. Methods: A literature search was undertaken using the PubMed and Web of Knowledge databases.
Elinor Elinor, Fiona J. Rowe
doaj +1 more source
BMJ Open, 2021 Objective To update data on strabismus and evaluate the changes in prevalence and patterns among preschoolers in eastern China over a period of 5 years.Design Nanjing Eye Study, a longitudinal population-based study.Setting Recruitment and testing in ...
Yue Wang +14 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source