Results 61 to 70 of about 3,720,590 (347)
Machine learning techniques for lipid nanoparticle formulation
A significant amount of effort has been poured into optimizing the delivery system that is demanded by novel therapeutic modalities. Lipid nanoparticle presents as a solution to transfect cells safely and efficiently with nucleic acid-based therapeutics.
Hao Li, Yayi Zhao, Chenjie Xu
doaj +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia +5 more
wiley +1 more source
Advancing solar energy applications with graphene: the potential of minimally oxidized graphene
Integrating carbon nanomaterials into solar energy technologies has emerged as a promising strategy to improve efficiency, scalability, and sustainability.
Qiang Chen +3 more
doaj +1 more source
Convergent multiples of convergent operators
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +3 more sources
Convergence of sectorial operators on varying Hilbert space
Convergence of operators acting on a given Hilbert space is an old and well studied topic in operator theory. The idea of introducing a related notion for operators acting on arying spaces is natural.
Mugnolo, Delio +2 more
core +2 more sources
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Developing functional solid polymer electrolytes (SPEs) is crucial for flexible, lightweight, and portable supercapacitors. This work presents an electrospinning approach to fabricate SPEs using poly(vinyl alcohol)-sodium chloride (PVA-NaCl) nanofibers ...
Ponnaiah Sathish Kumar +4 more
doaj +1 more source
9 pages, 7 ...
Pradas, Marc +3 more
openaire +3 more sources
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source

