Results 61 to 70 of about 2,731,647 (316)
, 2010 In this paper, we study the convergence behavior of distributed iterative algorithms with quantized message passing. We first introduce general iterative function evaluation algorithms for solving fixed point problems distributively.
Cui, Ying, Lau, Vincent K. N.
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Journal of Physics A: Mathematical and Theoretical, 2017 9 pages, 7 ...
Pradas, Marc +3 more
openaire +2 more sources
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
L\'evy-type processes: convergence and discrete schemes [PDF]
, 2017 We characterise the convergence of a certain class of discrete time Markov processes toward locally Feller processes in terms of convergence of associated operators.
Gradinaru, Mihai, Haugomat, Tristan
core
The convergence and partial convergence of alternating series [PDF]
Mathematics of Computation, 1980 The alternating series is Σ n = 1 ∞ j n f ( n ) = [ j ] f \Sigma _{n = 1}^\infty {j_n}f(n) = [j]f , with f a single-signed monotonic function of ...
openaire +2 more sources
FEBS Open Bio, EarlyView.Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao +7 more
wiley +1 more source
Electrically tunable metasurface perfect absorber for infrared frequencies
Nano Convergence, 2017 We theoretically investigate a metasurface perfect absorber based on indium-tin-oxide as active material. Our design scheme relies on conventional metal–oxide–semiconductor model and the Drude model. Inducing a voltage into the device causes a blue-shift
Gwanho Yoon +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui +3 more
wiley +1 more source
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source