Results 91 to 100 of about 166,325,679 (283)
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Convergence properties of numerical discretizations and regridding methods
Journal of Computational and Applied Mathematics, 1993 The paper is devoted to the study of difference schemes for the following two problems: (P1) \(-u_ x+s(x)=0\), \(u(0)=u_ 0 ...
Ferreira, J.A., De Oliveira, Paula
openaire +2 more sources
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
A dynamic convergence control scheme for the solution of the radial equilibrium equation in through-flow analyses [PDF]
, 2010 One of the most frequently encountered numerical problems in scientific analyses is the solution of non-linear equations. Often the analysis of complex phenomena falls beyond the range of applicability of the numerical methods available in the public ...
Templalexis, I. +3 more
core +1 more source
On a Bi-Parametric Family of Fourth Order Composite Newton–Jarratt Methods for Nonlinear Systems
Mathematics, 2019 We present a new two-parameter family of fourth-order iterative methods for solving systems of nonlinear equations. The scheme is composed of two Newton−Jarratt steps and requires the evaluation of one function and two first derivatives in each ...
Janak Raj Sharma +3 more
doaj +1 more source
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Linear Multistep Methods for Impulsive Differential Equations
Discrete Dynamics in Nature and Society, 2012 This paper deals with the convergence and stability of linear multistep methods for impulsive differential equations. Numerical experiments demonstrate that both the mid-point rule and two-step BDF method are of order p=0 when applied to impulsive ...
X. Liu, M. H. Song, M. Z. Liu
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng +4 more
wiley +1 more source
An Accelerated Sixth-Order Procedure to Determine the Matrix Sign Function Computationally
MathematicsThe matrix sign function has a key role in several applications in numerical linear algebra. This paper presents a novel iterative approach with a sixth order of convergence to efficiently compute this function.
Shuai Wang +4 more
doaj +1 more source