Midbrain PAG Astrocytes Modulate Mouse Defensive and Panic‐Like Behaviors
Astrocytes in the midbrain periaqueductal gray (PAG) dynamically encode threat intensity and shape defensive action selection in mice. Real‐time Ca2+ imaging reveals robust astrocytic activation during predator odor and CO2 exposure. Aberrant astrocytic Ca2+ overactivation disrupts goal‐directed escape, biases behavior toward freezing, and induces ...
Ellane Barcelon +10 more
wiley +1 more source
QLSA-MOEAD integration for precision task scheduling in heterogeneous computing environments. [PDF]
Saad A +3 more
europepmc +1 more source
Temporal and Cell‐Specific Regulation of Synaptic Homeostasis by the Chromatin Remodeler Chd1
Chd1, the Drosophila homologue of mammalian CHD2 ‐ a gene linked to autism, epilepsy, and intellectual disability, is required for synaptic homeostatic plasticity. Chd1 in glia is necessary for the rapid induction of synaptic homeostasis, whereas Chd1 in motoneurons, muscle, and glia is critical for long‐term maintenance.
Danielle T. Morency +19 more
wiley +1 more source
QRBT: Quantum Driven Reinforcement Learning for Scalable Blockchain Transaction Processing. [PDF]
Lella KK, Mallu SRK.
europepmc +1 more source
FLARE, a multimodal AI framework, combines pathology slides, radiology scans, and clinical reports to predict colorectal cancer outcomes, even when some tests are missing. Evaluated retrospectively in 1679 patients from four medical centers, it consistently achieved the best prognostic accuracy and clearly separated high‐ and low‐risk groups.
Linhao Qu +6 more
wiley +1 more source
The new rank-based concentration index: Further analysis and properties. [PDF]
Kvålseth TO.
europepmc +1 more source
Heuristically Adaptive Diffusion‐Model Evolutionary Strategy
Building on the mathematical equivalence between diffusion models and evolutionary algorithms, researchers demonstrate unprecedented control over evolutionary optimization through conditional diffusion. By training diffusion models to associate parameters with specific traits, they can guide evolution toward solutions exhibiting desired behaviors ...
Benedikt Hartl +3 more
wiley +1 more source
Extracting Weight of Evidence from p-Value via Bayesian Approach to Activation Likelihood Estimation Meta-Analysis. [PDF]
Costa T +4 more
europepmc +1 more source
A Wearable Brain–Computer Interface for Mitigating Car Sickness via Attention Shifting
Car sickness poses a major challenge in vehicular travel, yet effective nonpharmacological solutions are scarce. We developed a wearable, closed‐loop mindfulness BCI that uses real‐time EEG‐based neurofeedback to shift attention away from motion‐induced discomfort. Validated in real‐car experiments involving >100$>100$ susceptible individuals, over 83%
Jiawei Zhu +14 more
wiley +1 more source
Probabilistic Clustering Using Multivariate Growth Mixture Model in Clinical Settings-A Scleroderma Example. [PDF]
Kim JS +5 more
europepmc +1 more source

