Results 101 to 110 of about 3,698,697 (306)
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
On the gravitation and convergence of industry profit rates in Denmark, Finland, Italy and the US [PDF]
The hypotheses of profit rates gravitating around or converging towards a common value is tested using Danish, Finnish, Italian and US data. Both hypotheses are rejected for all the countries considered.
Andrea Vaona
core
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Rates of convergence for the posterior distributions of mixtures of Betas and adaptive nonparametric estimation of the density. [PDF]
In this paper, we investigate the asymptotic properties of nonparametric Bayesian mixtures of Betas for estimating a smooth density on [0, 1]. We consider a parametrization of Beta distributions in terms of mean and scale parameters and construct a ...
Rousseau, Judith
core
Segmentation of Shallow Slow Slip Events at the Hikurangi Subduction Zone Explained by Along-Strike Changes in Fault Geometry and Plate Convergence Rates. [PDF]
J Geophys Res Solid Earth, 2022 Perez-Silva A +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Nonlinearities in price convergence among Mercosur countries [PDF]
The aim of this paper is to analyse the existence of price convergence in Mercosur. Two variables are considered, Consumer Price Indices to assess convergence in the goods and services markets and real interest rates, to analyse convergence in the money ...
Javier Ordoñez, Juan Carlos Cuestas
core
Convergence rates of wavelet density estimation for negatively dependent sample
Journal of Inequalities and Applications, 2019 In this paper, linear and nonlinear wavelet estimators are defined for a density in a Besov space based on a negatively dependent random sample, and their upper bounds on Lp $L^{p}$ ( 1 ...
Junlian Xu
doaj +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
INFLATION CONVERGENCE IN CENTRAL AND EASTERN EUROPEAN ECONOMIES [PDF]
In this study, the degree of convergence of inflation rates of Central and East European economies to a variety of measures of European norm inflation is assessed using a range of econometric techniques.
Alina M. Spiru
core