Results 81 to 90 of about 13,863,967 (339)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Convergence rates in homogenization of p-Laplace equations
Boundary Value Problems, 2019 This paper is concerned with homogenization of p-Laplace equations with rapidly oscillating periodic coefficients. The main difficulty of this work is due to the nonlinear structure in this field concerning p-Laplace equations itself. Utilizing the layer
Jie Zhao, Juan Wang
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Fast Convergence Rates of Distributed Subgradient Methods With Adaptive Quantization
IEEE Transactions on Automatic Control, 2018 We study distributed optimization problems over a network when the communication between the nodes is constrained, and therefore, information that is exchanged between the nodes must be quantized.
Thinh T. Doan +2 more
semanticscholar +1 more source
Convergence rates of nonlinear Stokes problems in homogenization
Boundary Value Problems, 2019 In this paper, we study the convergence rates of solutions in homogenization of nonlinear Stokes Dirichlet problems. The main difficulty of this work is twofold.
Juan Wang, Jie Zhao
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Computer Methods in Applied Mechanics and Engineering, 2018 We present a novel blended B-spline method to construct bicubic/tricubic splines over unstructured quadrilateral and hexahedral meshes for isogeometric analysis.
Xiaodong Wei +7 more
semanticscholar +1 more source
Periodic Korovkin Theorem via $P_{p}^{2}$-Statistical $\mathcal{A}$-Summation Process
Universal Journal of Mathematics and Applications, 2022 In the current research, we investigate and establish Korovkin-type approximation theorems for linear operators defined on the space of all $% 2\pi $-periodic and real valued continuous functions on $% %TCIMACRO{\U{211d} }% %BeginExpansion \mathbb{R ...
Kamil Demirci +2 more
doaj +1 more source