Results 41 to 50 of about 3,698,697 (306)
This paper provides an introduction to the Stein method framework in the context of steady-state diffusion approximations. The framework consists of three components: the Poisson equation and gradient bounds, generator coupling, and moment bounds ...
Anton Braverman, J. G. Dai, Jiekun Feng
doaj +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Convergence rates of eigenvalue problems in perforated domains: the case of small volume
This paper is concerned with the Dirichlet eigenvalue problem for Laplace operator in a bounded domain with periodic perforation in the case of small volume.
Shen Zhongwei, Zhuge Jinping
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Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
A kind of univariate improved Shepard-Euler operators
In this paper, a kind of univariate Shepard-Euler operators is studied by combining the known Shepard operator with the generalized Taylor polynomial as the expansion in the Euler polynomials.
Wu Ruifeng
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Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Second Moment Convergence Rates for Uniform Empirical Processes
Let be a sequence of independent and identically distributed -distributed random variables. Define the uniform empirical process as , . In this paper, we get the exact convergence rates of weighted infinite series of .
Chen You-You, Zhang Li-Xin
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Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Information Bounds and Convergence Rates for Side-Channel Security Evaluators
Current side-channel evaluation methodologies exhibit a gap between inefficient tools offering strong theoretical guarantees and efficient tools only offering heuristic (sometimes case-specific) guarantees.
Loïc Masure +3 more
doaj +1 more source

