Results 51 to 60 of about 15,295,462 (264)

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Efficient implementation of LMS adaptive filter-based FECG extraction on an FPGA

Healthcare Technology Letters, 2020
In this Letter, the field programmable gate array (FPGA) implementation of a foetal heart rate (FHR) monitoring system is presented. The system comprises a preprocessing unit to remove various types of noise, followed by a foetal electrocardiogram (FECG)
Bhavya Vasudeva, Puneesh Deora, Puneesh Deora, Pradhan Mohan Pradhan, Sudeb Dasgupta, Sudeb Dasgupta   +5 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

INTERIOR GATEWAY PROTOCOL ROUTING PERFORMANCE COMPARISON OF THE VIRTUAL PRIVATE NETWORK BASED ON MULTI PROTOCOL LABEL SWITCHING AND DIRECT-LINK BACKUPSED ON MPLS AND DIRECT-LINK BACKUP

Jurnal Ilmiah SINERGI, 2019
The stability and convergence time become an essential factor in network availability performance. Multiprotocol Label Switching (MPLS) is one of the Virtual Private Network (VPN) technologies that can support the quality of communication media on the ...
Ida Nurhaida, Dimas Widya Putra Pratama, Remmy A. M. Zen, Hong Wei   +3 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Regional convergence in Italy: time series approaches [PDF]

This paper investigates the evolution of the gap between Italian regions and Italy as a whole during the period 1980-2007. We tested for the presence of the stochastic and β-convergence hypotheses using different time series approaches.
De Siano, Rita, D'Uva, Marcella
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Trade Liberalization and Regional Income Convergence in Mexico: a Time-Series Analysis [PDF]

We study the hypothesis of convergence amongst Mexican regions since 1940 with special interest in the post-trade liberalization period. A standard time-series convergence test shows that per capita income levels between the capital and the rest of the ...
Daniel Ventosa-Santaularia, Manuel Gomez
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Ghana's Economic Growth in perspective: A time series approach to Convergence and Growth Determinants [PDF]

Economic growth around the world has not been equal for a long time. Some economics grow faster while others grow slower. But economists have predicted that the slower growing economics will eventually converge with the faster growing economy as some ...
Baafi Antwi, Joseph
core