Results 81 to 90 of about 20,023,457 (377)

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Convergence Time Measurement Method of Active Noise Cancelling Headphones

Acoustics
The aim of this paper is to develop and describe an objective method for measuring the performance of headphones with active noise cancellation (ANC). The focus was on measuring both passive and active sound attenuation and determining the convergence ...
Agata Zatorska, Michał Łuczyński, Wojciech Bartnik   +2 more
doaj   +1 more source

Efficient implementation of LMS adaptive filter-based FECG extraction on an FPGA

Healthcare Technology Letters, 2020
In this Letter, the field programmable gate array (FPGA) implementation of a foetal heart rate (FHR) monitoring system is presented. The system comprises a preprocessing unit to remove various types of noise, followed by a foetal electrocardiogram (FECG)
Bhavya Vasudeva, Puneesh Deora, Puneesh Deora, Pradhan Mohan Pradhan, Sudeb Dasgupta, Sudeb Dasgupta   +5 more
doaj   +1 more source

The Impact of Community Structure on the Convergence Time of Opinion Dynamics

, 2017
We analyze the convergence time of opinion dynamics in a social network with community structure. Using matrix analysis, we prove that the convergence time is determined by the second largest eigenvalue modulus.
A. Lu, Chunhua Sun, Yezheng Liu
semanticscholar   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

Design of an Anti-Disturbance Luenberger Fault Estimator for the State of Charge Estimation of Lithium-Ion Batteries Based on Lipschitz Concept

Journal of Applied Science and Engineering
Battery management systems rely on an accurate estimate of the state of charge of lithiumion battery for safe and reliable operations. In this paper, we present a Luenberger observer suitable for nonlinear battery dynamics that are subject to practical ...
Qun Yu, Jing Xie
doaj   +1 more source

Long-time convergence of an Adaptive Biasing Force method [PDF]

, 2007
We propose a proof of convergence of an adaptive method used in molecular dynamics to compute free energy profiles. Mathematically, it amounts to studying the long-time behavior of a stochastic process which satisfies a non-linear stochastic differential
Lelievre, Tony, Otto, Felix, Rousset, Mathias, Stoltz, Gabriel   +3 more
core   +3 more sources

On SFTSM control with fixed‐time convergence

IET Control Theory & Applications, 2017
A singularity‐free terminal sliding mode (TSM) control scheme with fast and fixed‐time convergence for a class of second‐order non‐linear systems with matched uncertainties and external disturbances is proposed. A novel singularity‐free fast TSM (SFTSM) structure is constructed and the upper‐bound of convergence time is independent of initial states ...
Li, Huijie, Cai, Yuanli
openaire   +1 more source

On the rate of convergence of waiting times [PDF]

Journal of the Australian Mathematical Society, 1965
LetK(y) be a known distribution function on (−∞, ∞) and let {Fn(y),n= 0, 1,…} be a sequence of unknown distribution functions related bysubject to the initial conditionIf the sequence {Fn(y)} converges to a distribution functionF(y) thenF(y) satisfies the Wiener-Hopf ...
Cheong, C. K., Heathcote, C. R.
openaire   +2 more sources

Convergence Time for Unbiased Quantized Consensus Over Static and Dynamic Networks [PDF]

IEEE Transactions on Automatic Control, 2014
In this paper, the question of expected time to convergence is addressed for unbiased quantized consensus on undirected connected graphs, and some strong results are obtained.
S. Etesami, T. Başar
semanticscholar   +1 more source