Results 41 to 50 of about 1,116,121 (304)

Reliability & convergent validity tests summary.

open access: yes, 2022
Reliability & convergent validity tests summary.
Fahim Akhter (12015343)   +3 more
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Cross-Sectional and Longitudinal Validity of the Hughston Clinic Knee Questionnaire in Arthroscopic Meniscal Repair

open access: yesProceedings of Singapore Healthcare, 2010
Aim: To examine the cross-sectional and longitudinal convergent and discriminant validity and the sensitivity to change of the Hughston Clinic Knee Questionnaire (HCQ) in young adults with meniscal repair. Method: Seventeen young adults completed the HCQ
Yong Hao Pua PhD   +1 more
doaj   +1 more source

Construct reliability and convergent validity.

open access: yes, 2022
Construct reliability and convergent validity.
Muhammad Azeem Ashraf (11253087)   +6 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

CONSTRUCT VALIDITY AND CONCURRENT CRITERION VALIDITY OF FRONTAL SPLIT ON AN ELEVATED SURFACE TEST IN RHYTHMIC GYMNASTS

open access: yesScience of Gymnastics Journal
Flexibility is a foundational motor skill in rhythmic gymnastics and is crucial for successful performance. While existing flexibility assessments, such as the frontal splits on an elevated surface, have been used in the field for years, psychometric ...
Ahsen Büyükaslan, Maja Pajek
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Composite reliability and convergent validity.

open access: yes, 2021
Composite reliability and convergent validity.
Syed Sohaib Zubair (11785527)   +2 more
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

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