Results 61 to 70 of about 172,625 (266)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Degradation of Anthracene by Immobilizing Laccase From Trametes Versicolor onto Chitosan Beads and Hyacinth Plant

open access: yesAl-Mustansiriyah Journal of Science, 2020
Polycyclic aromatic hydrocarbons (PAHs) are recognized as a toxic, mutagenic and/or carcinogenic compounds, and their pollution of soil and aquifer is of increasing environmentally risk. Laccases (E.C.
Ali A. Taha   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

“It's hard to talk to a computer, I get it”: An exploratory analysis of clinician connection-building communication practices in rural telepalliative care encounters

open access: yesPEC Innovation
Context/Objectives: Establishing human connection is critical during serious illness conversations, however the sensory and relational environment of telehealth may require innovative communication practices for clinicians, patients, and families to do ...
Elise C. Tarbi   +6 more
doaj   +1 more source

ПРИМЕНЕНИЕ ОПЕРАТИВНОЙ ПСИХОДИАГНОСТИКИ ДЛЯ ПРЕДОТВРАЩЕНИЯ ПРОТИВОПРАВНЫХ ДЕЙСТВИЙ В МЕСТАХ МАССОВОГО СКОПЛЕНИЯ ГРАЖДАН

open access: yesНаучно-педагогическое обозрение, 2017
Рассматривается система обеспечения безопасности, действующая как оперативная триада «предупреждение – предотвращение – пресечение». Особое внимание уделено именно предупреждению противоправных действий и выявлению лиц, имеющих противоправные намерения ...
Астахова Армини Аветиковна   +1 more
doaj   +1 more source

Conversation Analysis in Tamil Speaking Male Children

open access: yesJournal of Indian Speech Language & Hearing Association, 2017
Introduction The present study aims to profile the conversation behaviors of typically developing Tamil speaking male children in the age range of 3–5 and 7–9 years.
Sathya Harinath   +1 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Conversation: What, How, Where, and Why is Speculation?

open access: yesFafnir, 2023
Fafnir is an academic journal focusing on research of speculative fiction, a popular spectrum of genres that has absolutely nothing to do with financial speculation, speculative philosophy, or speculative computing – or does it?
Essi Varis   +3 more
doaj  

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