Results 41 to 50 of about 32,444 (241)

My anesthesia Choice-HF: development and preliminary testing of a tool to facilitate conversations about anesthesia for hip fracture surgery

open access: yesBMC Anesthesiology
Background Patients often desire involvement in anesthesia decisions, yet clinicians rarely explain anesthesia options or elicit preferences. We developed My Anesthesia Choice-Hip Fracture, a conversation aid about anesthesia options for hip fracture ...
Mark D. Neuman   +4 more
doaj   +1 more source

My Whole Life in Telephones

open access: yesInternational Journal of Qualitative Methods, 2018
In this article, I address a methodological issue that has come into focus after the advent of the “material turn”; the matter of how to study historical, sociomaterial practices.
Mette Simonsen Abildgaard
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Adaptation and Implementation of Pictorial Conversation Aids for Early-Stage Breast Cancer Surgery and Reconstruction: A Quality Improvement Study

open access: yesPatient Preference and Adherence, 2023
Marie-Anne Durand,1– 3 Marie Bannier,4 Marie-Anastasie Aim,5,6 Julien Mancini7 1CERPOP, Université de Toulouse, Inserm, Université Toulouse III Paul Sabatier, Toulouse, France; 2The Dartmouth Institute for Health Policy & Clinical Practice, Dartmouth ...
Durand MA, Bannier M, Aim MA, Mancini J
doaj  

An Interview with Professor Lance Lanyon

open access: yesVeterinary Evidence, 2016
Professor Lance Lanyon recently published an article in Veterinary Record (Lanyon, 2016) proposing a nationwide Evidence Based Veterinary Medicine (EBVM) system of veterinary-practice data collection, management and interrogation. The goal is to use data
Lance Lanyon
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Laughter Classification Using Deep Rectifier Neural Networks with a Minimal Feature Subset

open access: yesArchives of Acoustics, 2016
Laughter is one of the most important paralinguistic events, and it has specific roles in human conversation. The automatic detection of laughter occurrences in human speech can aid automatic speech recognition systems as well as some paralinguistic ...
Gábor GOSZTOLYA   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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