Results 61 to 70 of about 1,241,629 (201)

Caracterización de parámetros fenotípicos, morfométricos y evaluación productiva de Cavia porcellus procedentes de diferentes zonas del Ecuador

Revista Científica y Tecnológica UPSE
La producción de cuyes forma parte de la ancestralidad de los países andinos, por el aporte socioeconómico y a la seguridad alimentaria. Con el objetivo de evaluar el efecto de la procedencia de estos animales en los parámetros fenotípicos, morfométricos
Luis Alonso Chicaiza Sánchez, Silvia Paola Gualavisi Pulamarin, Patricia Marcela Andrade Aulestia, Edilberto Chacón Marcheco, Rafael Alfonso Garzón Jarrín   +4 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Experiencias del Hash en la vida informática

Revista de Iniciación Científica, 2018
Este artículo resalta el proceso de generación de llaves codificadas y, los métodos Hash asociados al mismo y las colisiones que ocurren tras dicha transformación. La tecnología dentro de este contexto está orientada primordialmente a buscar diferentes
Maxs Barrera, Luis Santana, Radames Pereira, María Yahaira Tejedor   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Las transformaciones semióticas para analizar estrategias de solución de problemas de interpretación y representación

Pensamiento Americano
Introducción: La teoría de registro de representaciones semióticas establece que el uso de sistemas de signos que permiten las actividades cognitivas de formación, conversión y tratamiento son esenciales para tener acceso a los objetos o procesos ...
Jesús David Berrío Valbuena, Sonia Valbuena Duarte, Rafael Sánchez Anillo   +2 more
doaj   +1 more source

Reelaboración de los protestantismos en el municipio fronterizo de Las Margaritas, Chiapas

Revista Pueblos y Fronteras Digital, 2019
El protestantismo en Chiapas ha sido objeto de investigación desde finales de la década de 1980. Hasta entonces no se había considerado como un tema importante para explicar las transformaciones sociales y las identidades socioculturales, sobre todo de ...
Irene Sánchez Franco
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source