Results 71 to 80 of about 1,295,542 (267)
Proceedings of the 26th ACM Conference on Economics and ComputationWe study the optimal placement of advertisements for interactive platforms like conversational AI assistants. Importantly, conversations add a feature absent in canonical search markets -- time. The evolution of a conversation is informative about ad qualities, thus a platform could delay ad delivery to improve selection.
Martino Banchio +2 more
openaire +4 more sources
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
A Novel Zeroing Neural Network for the Effective Solution of Supply Chain Inventory Balance Problems
ComputationThe issue of inventory balance in supply chain management represents a classic problem within the realms of management and logistics. It can be modeled using a mixture of equality and inequality constraints, encompassing specific considerations such as ...
Xinwei Cao +2 more
doaj +1 more source
Technological and Economic Development of Economy, 2008 The article deals with the problems of investment development of air companies. The author examines the aspects of modelling of investment solutions under conditions of developing aviation business, giving methods of modelling of demand, including those ...
Irina Arljukova
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The Conversion of Heritage and the Heritage of Conversion: Two Case Studies from Trentino
ReligionsThis article explores two cases of architectural conversion within the TESEO project: the transformation of a Catholic church into an Orthodox church in Trento and the adaptation of a farmstead into a Buddhist temple in the Molin Valley, Trentino.
Silvia Omenetto, Giuseppe Tateo
doaj +1 more source