Results 61 to 70 of about 365,980 (259)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Chinese Journal of Contemporary Neurology and Neurosurgery, 2023 Objective To summarize the clinical characteristics of children with functional neurological disorder (FND) presented with motor symptoms. Methods and Results Total 18 children with FND mainly manifested by motor symptoms were admitted to Department of ...
TANG Ya⁃nan, WEI Hong⁃ling, XING Yan
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Spin-charge conversion in disordered two-dimensional electron gases lacking inversion symmetry
, 2017 We study the spin-charge conversion mechanisms in a two-dimensional gas of electrons moving in a smooth disorder potential by accounting for both Rashba-type and Mott's skew scattering contributions. We find that quantum interference effects between spin-
Cazalilla, Miguel +2 more
core +1 more source
Somatic symptom disorder in dermatology [PDF]
, 2017 Somatic symptom disorder (SSD) is defined by the prominence of somatic symptoms associated with abnormal thoughts, feelings, and behaviors related to the symptoms, resulting in significant distress and impairment.
Levenson, James L. +2 more
core +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Diagnosis and treatment of functional limb weakness
Chinese Journal of Contemporary Neurology and Neurosurgery, 2023 Functional limb weakness is a common functional motor disorder, and its clinical diagnosis is mainly based on the medical history, neurological examinations and patients' positive signs.
YIN Dou, WANG Gang, WANG Ji⁃xian
doaj +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Superconductor-to-normal transition in finite nanowires [PDF]
, 2008 In this paper we discuss the interplay of quantum fluctuations and dissipation in uniform superconducting nanowires. We consider a phenomenological model with superconducting and normal components, and a finite equilibration rate between these two-fluids.
Demler, Eugene, Oreg, Yuval, Refael, Gil
core +2 more sources
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source