Results 61 to 70 of about 412,273 (267)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

The crystal structure of bis(2-(2,2,2-trifluoroacetyl)-3,4-dihydronaphthalen-1-olato-κ2O,O′)copper(II), C24H16CuF6O4

Zeitschrift für Kristallographie - New Crystal Structures, 2017
C24H16CuF6O4, triclinic, P1̄ (no. 2), a = 6.5651(7) Å, b = 9.4145(10) Å, c = 9.5014(11) Å, α = 68.668(10)°, β = 77.063(9)°, γ = 86.847(9)°, V = 532.91(11) Å3, Z = 1, Rgt(F) = 0.0596, wRref(F2) = 0.1477, T = 293 K.
Shao HaiFeng, Hou YanJun
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

The crystal structure of [6-methoxy-2-(2,2,2-trifluoroacetyl)-3,4-dihydronaphthalen-1(2H)-one]difluoroborane, C13H10BF5O3

Zeitschrift für Kristallographie - New Crystal Structures, 2017
C13H10BF5O3, triclinic, P1̄ (no. 2), a = 7.737(2) Å, b = 7.8600(19) Å, c = 11.803(3) Å, α = 82.03(2)°, β = 76.91(2)°, γ = 69.69(2)°, V = 654.2(3) Å3, Z = 2, Rgt(F) = 0.0471, wRref(F2) = 0.1203, T = 293 K.
Bai JinYuan, Hou YanJun
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Comparative Study of Liquid Biodiesel From Sterculia foetida (Bottle Tree) Using CuO-CeO2 and Fe2O3 Nano Catalysts

Frontiers in Energy Research, 2019
This study examined the potential of nanocatalyst CuO-CeO2 and Fe2O3 for efficient conversion of Sterculia foetida seed Oil into biodiesel. S. foetida contains 40% oil content and low free fatty acid value (0.18 mg KOH/g).
Maryam Tanveer Akhtar, Mushtaq Ahmad, Anjuman Shaheen, Muhammad Zafar, Riaz Ullah, Maliha Asma, Shazia Sultana, Mamoona Munir, Neelam Rashid, Khafsa Malik, Muhammad Saeed, Amir Waseem   +11 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Superior Multimodal Luminescence in a Stable Single‐Host Nanomaterial with Large‐Scale Synthesis for High‐Level Anti‐Counterfeiting and Encryption

Advanced Science
Multimode luminescent materials exhibit tunable photon emissions under different excitation or stimuli channels, endowing them high encoding capacity and confidentiality for anti‐counterfeiting and encryption.
Bingyin Kong, Gencai Pan, Mengke Wang, Hongye Tang, Zhipeng Lv, Shiyu Sun, Yuxin Luo, Wenwu You, Wen Xu, Yanli Mao   +9 more
doaj   +1 more source