Results 71 to 80 of about 1,475,197 (300)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

The crystal structure of bis(2-(2,2,2-trifluoroacetyl)-3,4-dihydronaphthalen-1-olato-κ2O,O′)copper(II), C24H16CuF6O4

Zeitschrift für Kristallographie - New Crystal Structures, 2017
C24H16CuF6O4, triclinic, P1̄ (no. 2), a = 6.5651(7) Å, b = 9.4145(10) Å, c = 9.5014(11) Å, α = 68.668(10)°, β = 77.063(9)°, γ = 86.847(9)°, V = 532.91(11) Å3, Z = 1, Rgt(F) = 0.0596, wRref(F2) = 0.1477, T = 293 K.
Shao HaiFeng, Hou YanJun
doaj   +1 more source

Optimisation of DSF and SOA based phase conjugators by incorporating noise-suppressing fibre gratings

, 1997
We compare the performance of dispersion-shifted-fibre (DSF) and semiconductor-optical-amplifier (SOA) based phase conjugators for a 10 Gb/s non-return-to-zero system with respect to conversion efficiency, noise figure and distortion.
Cole, M.J., Geiger, H., Laming, R.I., Reekie, L., Set, S.Y.   +4 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Comparative Study of Liquid Biodiesel From Sterculia foetida (Bottle Tree) Using CuO-CeO2 and Fe2O3 Nano Catalysts

Frontiers in Energy Research, 2019
This study examined the potential of nanocatalyst CuO-CeO2 and Fe2O3 for efficient conversion of Sterculia foetida seed Oil into biodiesel. S. foetida contains 40% oil content and low free fatty acid value (0.18 mg KOH/g).
Maryam Tanveer Akhtar, Mushtaq Ahmad, Anjuman Shaheen, Muhammad Zafar, Riaz Ullah, Maliha Asma, Shazia Sultana, Mamoona Munir, Neelam Rashid, Khafsa Malik, Muhammad Saeed, Amir Waseem   +11 more
doaj   +1 more source

Successful reprogramming of epiblast stem cells by blocking nuclear localization of β-catenin. [PDF]

, 2014
Epiblast stem cells (EpiSCs) in mice and rats are primed pluripotent stem cells (PSCs). They barely contribute to chimeric embryos when injected into blastocysts.
Hayama, Tomonari, Masaki, Hideki, Murayama, Hideyuki, Nakauchi, Hiromitsu, Sato, Hideyuki, Yamaguchi, Tomoyuki   +5 more
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Superior Multimodal Luminescence in a Stable Single‐Host Nanomaterial with Large‐Scale Synthesis for High‐Level Anti‐Counterfeiting and Encryption

Advanced Science
Multimode luminescent materials exhibit tunable photon emissions under different excitation or stimuli channels, endowing them high encoding capacity and confidentiality for anti‐counterfeiting and encryption.
Bingyin Kong, Gencai Pan, Mengke Wang, Hongye Tang, Zhipeng Lv, Shiyu Sun, Yuxin Luo, Wenwu You, Wen Xu, Yanli Mao   +9 more
doaj   +1 more source

Comportamento ingestivo e desempenho de ovinos em pastagem de azevém anual (Lolium multiflorum Lam.) com diferentes massas de forragem Ingestive behaviour and performance of sheep grazing Italian ryegrass (Lolium multiflorum Lam.) pasture with different herbage masses

Revista Brasileira de Zootecnia, 2007
Objetivou-se avaliar o comportamento ingestivo e o desempenho de ovinos em pastagem de azevém anual (Lolium multiflorum Lam.) sob pastejo contínuo e com diferentes massas de forragem: baixa: 1.000 a 1.200 kg/ha MS; intermediária: 1.400 a 1.600 kg/ha MS ...
Juliano Roman, Marta Gomes da Rocha, Cleber Cassol Pires, Denise Adelaide Gomes Elejalde, Mircon Giovani Kloss, Renato Alves de Oliveira Neto   +5 more
doaj   +1 more source