Results 81 to 90 of about 16,435,716 (297)

Calibration system for portable alpha and beta contamination monitors

Radiation Protection and Environment
Evaluation of contamination is done by various contamination monitoring instruments. The calibration of these instruments is essential for evaluating their performance over time.
Athira B. Varrier, T. P. Preetha, M. Menaka   +2 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

High-resolution transcriptional dissection of in vivo Atoh1-mediated hair cell conversion in mature cochleae identifies Isl1 as a co-reprogramming factor

PLoS Genetics, 2018
In vivo direct conversion of differentiated cells holds promise for regenerative medicine; however, improving the conversion efficiency and producing functional target cells remain challenging.
T. Yamashita, Fei Zheng, D. Finkelstein, Zoe Kellard, Robert A. Carter, Celeste D Rosencrance, Ken Sugino, J. Easton, Charles Gawad, J. Zuo   +9 more
semanticscholar   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Scientific and technical assistance to the evaluation of the safety of calcidiol monohydrate as a novel food

EFSA Journal
EFSA was asked by the European Commission to provide scientific assistance with respect to the EFSA adopted scientific opinion on ‘Safety of calcidiol monohydrate produced by chemical synthesis as a novel food pursuant to Regulation (EU) 2015/2283 ...
European Food Safety Authority (EFSA), Dominique Turck, Harry J. McArdle, Androniki Naska, Monika Neuhäuser‐Berthold, Giovanni Passeri, Ionut Craciun, Ruth Roldán‐Torres, Silvia Valtueña Martínez   +8 more
doaj   +1 more source

Efficacy of Onabotulinum Toxin A (Botox) versus Abobotulinum Toxin A (Dysport) Using a Conversion Factor (1 : 2.5) in Treatment of Primary Palmar Hyperhidrosis

Dermatology research and practice, 2013
Background. Two preparations of botulinum A toxin (BTX-A) are commercially available for the treatment of palmar hyperhidrosis (PPH): Botox (Allergan; 100 U/vial) and Dysport (Ipsen Limited; 500 U/vial), which are not bioequivalent.
H. E. El Kahky, H. Diab, D. Aly, N. Farag   +3 more
semanticscholar   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Stacked volume conversion factor for geometric volume of Eucalyptus sp.

Agro@mbiente On-line, 2019
Post-harvest, wood volume can be calculated with a stacking factor which can be influenced by diameter classes involved. Consequently, the following question arises: there is a difference between the volume conversion factor for stacked to geometric ...
André Salgado de Andrade Sandim, Ariadna Coelho Mota, Mario Lima dos Santos, Welton dos Santos Barros, Beatriz Cordeiro Costa, Vanda Maria Sales de Andrade   +5 more
doaj   +1 more source