Results 101 to 110 of about 13,923,371 (387)

Revisiting the Cosmic Star Formation History: Caution on the Uncertainties in Dust Correction and Star Formation Rate Conversion

, 2013
The cosmic star formation rate density (CSFRD) has been observationally investigated out to redshift z~10. However, most of theoretical models for galaxy formation underpredict the CSFRD at z>1.
Akio K. Inoue, Bower, Calzetti, Casey, Chary, Fioc, Garnett, Hopkins, Hopkins, Hopkins, Horiuchi, Karim, Kashikawa, Kistler, Kobayashi, Kobayashi, Kodama, Lacey, Le Floc'h, Lilly, Madau, Madau, Masakazu A. R. Kobayashi, Murphy, Nagamine, Nagashima, Nagashima, Oesch, Pérez-González, Reddy, Strigari, Tominaga, Wang, Wyder, Yabe, Yahagi, Yoshiyuki Inoue, Yüksel   +37 more
core   +1 more source

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

FEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri, Andrea Lapucci, Giuseppe Orsomando, Nadia Raffaelli, Alberto Chiarugi, Daniela Buonvicino   +5 more
wiley   +1 more source

Eye Donation Awareness and Conversion Rate in Hospital Cornea Retrieval Programme in a Tertiary Hospital of Central India.

Journal of clinical and diagnostic research : JCDR, 2017
INTRODUCTION Corneal blindness accounts for 6-8 million blinds in the world. In India, it is estimated that there are approximately 6.8 million people who have vision less than 6/60 in at least one eye due to corneal diseases.
Bhavana Sharma, U. Shrivastava, Kavita Kumar, R. Baghel, Farhana Khan, S. Kulkarni   +5 more
semanticscholar   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Research on the Decomposition Characteristics of Methane Hydrates Exploited by the NH₄Cl/NaNO₂ System

Energies
Considering the influence of the system conversion rate on hydrate decomposition kinetics and energy utilization during the decomposition process of pure methane hydrate in the NH4Cl/NaNO2 system (an in situ chemical heat generation system), this study ...
Jihong Zhang, Yi Wan, Ming Li, Yanan Wang, Xinjian Tan   +4 more
doaj   +1 more source

The mechanism of pyridine hydrogenolysis on molybdenum-containing catalysts : IV. The conversion of piperidine [PDF]

, 1973
The conversion of piperidine was investigated on a CoO-MoO3-Al2O3 catalysts as a function of the temperature, reaction time, initial piperidine partial pressure and the hydrogen pressure.\ud \ud At 60 atm of hydrogen and conversions below 50% piperidine ...
Mars, P., Neyens, W.J., Sonnemans, J.
core   +2 more sources

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

FEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia, Eric Catalina‐Hernandez, Maialen Cabrerizo‐Idiazabal, Ramon Barnadas‐Rodríguez, Mario Lopez‐Martin, Alex Peralvarez‐Marin   +5 more
wiley   +1 more source

Conversion rate of laparoscopic to open cholecystectomy

Yemeni Journal for Medical Sciences, 2009
Purpose: to audit the conversion rate and identify the conversion reasons necessitating Yemeni laparoscopists to convert laparoscopic cholecystectomy to open procedure.
Saeed Hadi Al-Bahlooli, Ahmed Al-Malahi, Nagi Homesh Ghallab, Abdulelah Shuga'a Al-Dain, Ali A. Al Sabahi   +4 more
doaj   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source