This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Multidirectional motion estimation algorithm for frame rate up-conversion
In this paper, we propose a new motion estimation algorithm for motion-compensated frame rate up-conversion. To reduce computational complexity, it constructs a hierarchical structure using Gaussian image pyramid and unidirectionally estimates motion ...
Yu Songhyun, Jeong Jechang
doaj +1 more source
Constant Conversion Rate of Endolysosomes Revealed by a pH-Sensitive Fluorescent Probe. [PDF]
Chen R +6 more
europepmc +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
The way of goods ranking increasing conversion rate and order gross margin on online store
There is online store goods ranking problem observed and solving method is proposed.
V.L. Flaks
doaj
Factors Associated with Prescription-to-Vaccination Conversion and Timeliness: A Real-World Analysis
Background: This study evaluated vaccine prescription conversion and identified associated factors in Henan Province, China, during 2025. Methods: The study was conducted in Lingbao City, Henan Province.
Mengru Xiao +8 more
doaj +1 more source
Effect of metal ion stimulators on the conversion rate of whole-cell biocatalyst.
(A) Effect of different metal ions on the conversion rate of the biocatalyst; (B) Effect of Mn2+ concentration on the conversion rate of the biocatalyst.
Xian Zhang (191440) +7 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Co-Generation of C2+ Hydrocarbons and Synthesis Gas from Methane and Carbon Dioxide using Dielectric-Barrier Discharge Plasma Reactor without Catalyst at Low Temperature [PDF]
Co-generation of C2+ hydrocarbons and synthesis gas from methane and carbon dioxide has been an important issue in tackling the global warming effects from the two greenhouse gases.
Istadi, I., Saidina Amin, N.A.
core +1 more source

