Results 101 to 110 of about 892,678 (303)
Independent stratum formation on the avian sex chromosomes reveals inter-chromosomal gene conversion and predominance of purifying selection on the w chromosome [PDF]
, 2014 We used a comparative approach spanning three species and 90 million years to study the evolutionary history of the avian sex chromosomes. Using whole transcriptomes, we assembled the largest cross-species dataset of W-linked coding content to date.
Wright, Alison E +9 more
core +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Conversion factors : a discussion of alternate rates and corresponding weights [PDF]
The significant operational implications underlying the Bank's estimates of per capita GNP, represent important considerations in systematizing the use of official rates in determining the exchange rate to be used in the Atlas methodology.
Hee, Michael
core
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Limited impact of within-vector ecology on the evolution of malaria parasite transmission investment
Frontiers in MalariaMalaria parasites spend part of their life in a vertebrate host and the rest in an arthropod vector and must successfully navigate both environments to gain fitness.
Amber Gigi Hoi +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Journal of Health Science and Medical Research (JHSMR)Objective: This study aimed to evaluate the effect of difficult common bile duct (CBD) stone on conversion rate of Laparoscopic cholecystectomy (LC). In addition, this study evaluated the effect of difficult CBD stone on operative time and complications ...
Thana Boonsinsukh +6 more
doaj +1 more source
AREA EFFICIENT FRACTIONAL SAMPLE RATE CONVERSION ARCHITECTURE FOR SOFTWARE DEFINED RADIOS [PDF]
ICTACT Journal on Communication Technology, 2014 The modern software defined radios (SDRs) use complex signal processing algorithms to realize efficient wireless communication schemes. Several such algorithms require a specific symbol to sample ratio to be maintained.
Latha Sahukar, M. Madhavi Latha
doaj
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source