Results 51 to 60 of about 3,607 (265)

ZVZCS PWM DC-DC Converter with Energy Recovery Clamp

open access: yesAdvances in Electrical and Electronic Engineering, 2008
This paper presents research motivated by industrial demand for special traction drive topology devoted tominimization of traction transformer weight against topology with classical 50Hz traction transformer.
Jaroslav Durdik, Vladimir Ruscin
doaj  

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Research on Fire Suppression Characteristics of Compressed Air Foams in Full-Scale 220 kV Converter Transformer

open access: yesFire
To study the fire behavior of UHVDC (ultra-high-voltage direct current) converter transformers and the effectiveness of CAFs (compressed air foams) in suppressing fires, a full-scale model of a 220 kV converter transformer fire was constructed. The model
Yike Guo   +6 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Research on active damping voltage control considering leakage inductance of FOVRT transformer

open access: yesInternational Journal of Electrical Power & Energy Systems
The Flexible on-load voltage regulating transformer (FOVRT) is realized through the integration of a small power converter with the conventional on-load voltage regulator transformer.
Longfei Sun   +7 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

The Simulation of the Traction Drive with Middle-Frequency Transformer

open access: yesAdvances in Electrical and Electronic Engineering, 2008
This paper presents research motivated by industrial demand for special traction drive topology devoted to minimization of traction transformer weight against topology with classical 50Hz traction transformer.
Pavel Drabek   +3 more
doaj  

A Novel Structure of Variable Inductance High-Frequency Transformer for Power Level Enhancement in Dual-Active-Bridge Converters

open access: yesEnergies
This study presents a novel structure proposal of a variable inductance high-frequency transformer for enhancement power level of a dual-active-bridge (DAB) converter.
Cheol-Woong Choi   +5 more
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

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