Results 51 to 60 of about 118,684 (252)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Using an Integrated Script Control Unit (ISCU) to Assist the Power Electronics Education
Energies, 2017 An integrated script control unit (ISCU) is invented to work as the digital controller in power electronics educations. The ISCU mainly consists of two parts, a control board and computer software.
Zhigang Gao, Qi Lu
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Stabilizing control for power converters connected to transmission lines [PDF]
, 2007 This paper proposes a switching control strategy for the set-point stabilization of a power converter connected via a transmission line to a resistive load.
Zainea, Marius +10 more
core +2 more sources
Advances in Electrical and Computer Engineering, 2010 This paper investigates the influence of the parameters of the machine and of the soft starter on the dynamics of the induction machine start. In order to evaluate the effects of this variation we have used a design of experiments (DOE).
POPA, G. N. +3 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
IEEE AccessPower Factor Correction (PFC) is crucial for the efficient operation of Switched Reluctance Motor (SRM) converters, as it enhances energy utilization and minimizes system losses.
Deepak Mohanraj +3 more
doaj +1 more source
Advances in Electrical and Computer Engineering, 2016 Multicarrier based PWM switching patterns are commonly utilized to control Cascaded H-bridge (CHB) inverters. The main contribution of this paper is to comprehensively investigate the effect of various multicarrier based PWM techniques on harmonic ...
HAMEDANI, P., SHOULAIE, A.
doaj +1 more source