Results 231 to 240 of about 497,650 (327)

TSHR‐Targeting Nucleic Acid Aptamer Treats Graves' Ophthalmopathy via Novel Allosteric Inhibition

Advanced Science, EarlyView.
This study presents YC3, a novel inhibitory TSHR‐targeting aptamer, as a promising therapeutic for Graves' ophthalmopathy (GO). YC3 suppresses pathological phenotypes in human orbital fibroblasts and improves outcomes in GO mice by binding to a previously unidentified allosteric site on TSHR, demonstrating the potential of aptamers in advancing ...
Yanchen Zhang, Ende Wu, Weibin Liu, Ling Zeng, Neng Ling, Hongmei Wang, Zhixing Li, Shuang Yao, Tonghe Pan, Xuanwen Li, Yate Huang, Xiaojing Li, Yunhai Tu, Wentao Yan, Jianzhang Wu, Mao Ye, Wencan Wu   +16 more
wiley   +1 more source

Data‐Driven Printability Modeling of Hydrogels for Precise Direct Ink Writing Based on Rheological Properties

Advanced Science, EarlyView.
A predictive model for 3D printability is developed by integrating rheological analysis, including the Large Amplitude Oscillatory Shear (LAOS) test, with machine learning. With prediction errors under 10%, the model shows that post‐extrusion recovery controls horizontal printability, while high‐strain‐rate nozzle flow dictates vertical printability ...
Eun Hui Jeong, Jiho Choi, Han Bi Park, Ji Woo Lee, Seo Yeon Bae, Byoung Soo Kim, ChangKyu Yoon, Jun Dong Park   +7 more
wiley   +1 more source

Cellular Hallmarks From Volume Electron Microscopy Reveal Developmental Progression of Plasmodium Ookinetes

Advanced Science, EarlyView.
This article presents a detailed ultrastructural cell atlas of Plasmodium ookinete development using advanced volume electron microscopy (v) techniques. It defines seven distinct developmental stages, revealing complex organelle interactions and offering new insights into parasite differentiation.
Nedal Darif, Marco Rheinnecker, Kolja Hildenbrand, Thanat Chookajorn, Lilian P. Dorner, Jean‐Karim Hériché, Sara Henriksson, Charlotta Funaya, Franziska Hentzschel, Linda Sandblad, Oliver Billker, Yannick Schwab, Friedrich Frischknecht   +12 more
wiley   +1 more source

A Shape‐Adaptive, Performance‐Programmable, Self‐Healable and On‐Demand Destructible Robotic Skin via Self‐Strengthening Dynamic Silicone

Advanced Science, EarlyView.
Enabled by the distinctive inter‐ and intra‐chain siloxane exchange in commercially available silicones as the dielectric layer, the omni‐adaptive robotic skin (OmniAdapt) integrates multiple advanced functionalities: programmable sensing performance via the self‐stiffening dielectric material, application as BPM sensor, shape adaptivity for electronic
Wusha Miao, Lara S. Laamari, Jing Yu, Sanjay Schreiber, Lukas Heer, Jiacheng Cui, Jiayuan Huang, Hedan Bai   +7 more
wiley   +1 more source

Vector-Valued Convex Functions

Mustapha Laayouni
openalex   +1 more source

Mechanism‐Aware Digital Twin for High‐Temperature Creep Prediction in Mo–Re Alloys

Advanced Science, EarlyView.
A digital twin framework enables real‐time monitoring of creep in refractory alloys and reveals dislocation‐drag‐induced Re segregation to grain boundaries. Inspired by this, La2O3 dispersion is introduced to suppress dislocation motion — concurrently mitigating Re segregation and enhancing creep resistance.
Jinhan Xu, Xuan Chen, Xiaodan Bai, Chengyu Ding, Guisen Liu, Yuanjun Sun, Hongxiang Zong, Xiangdong Ding   +7 more
wiley   +1 more source

New criteria for functions to be in a class of p-valent alpha convex functions. [PDF]

ScientificWorldJournal, 2013
Arif M, Ayaz M, Aouf MK.
europepmc   +1 more source

A subclass of close-to-convex functions subordinate to a bilinear transformation

, 2017
Gagandeep Singh, Gurcharanjit Singh
openalex   +1 more source

Fresnel Magnetic Imaging of Ultrasmall Skyrmion Lattices

Advanced Science, EarlyView.
This study uncovers periodic contrast reversal in ultrasmall skyrmion lattice imaging through defocus‐modulated Fresnel magnetic microscopy, elucidating its origin in the sinusoidal contrast transfer function mechanism and providing fundamental insights into defocus‐mediated phase‐to‐intensity conversion processes in nanoscale magnetic imaging ...
Yongsen Zhang, Wei Liu, Meng Shi, Yaodong Wu, Jialiang Jiang, Sheng Qiu, Huanhuan Zhang, Hui Han, Mingliang Tian, Haifeng Du, Shouguo Wang, Jin Tang   +11 more
wiley   +1 more source

A general topology approach to the study of differentiability of convex functions in Banach spaces

, 1978
Petar S. Kenderov
openalex   +1 more source