Results 61 to 70 of about 205,588 (289)
Accurate knowledge of the flow rate is essential for hydraulic systems, enabling the calculation of hydraulic power when combined with pressure measurements. These data are crucial for applications such as predictive maintenance.
Faras Brumand-Poor +3 more
doaj +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
As gravity exploration technology advances, gravity gradient measurement is becoming an increasingly important method for gravity detection. Airborne gravity gradient measurement is widely used in fields such as resource exploration, mineral detection ...
Shuai Zhou +3 more
doaj +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
A Computational Method for Subdivision Depth of Ternary Schemes
Subdivision schemes are extensively used in scientific and practical applications to produce continuous shapes in an iterative way. This paper introduces a framework to compute subdivision depths of ternary schemes.
Faheem Khan +4 more
doaj +1 more source
For a complete lattice $L$ and a relational structure $\mathfrak{X}=(X,(R_i)_I)$, we introduce the convolution algebra $L^{\mathfrak{X}}$. This algebra consists of the lattice $L^X$ equipped with an additional $n_i$-ary operation $f_i$ for each $n_i+1$-ary relation $R_i$ of $\mathfrak{X}$.
Harding, John +2 more
openaire +3 more sources
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Skeleton‐based action recognition has received much attention and achieved remarkable achievements in the field of human action recognition. In time series action prediction for different scales, existing methods mainly focus on attention mechanisms to ...
Siyue Lei +5 more
doaj +1 more source
Driven by Drones: Improving Mangrove Extent Maps Using High-Resolution Remote Sensing
This study investigated how different remote sensing techniques can be combined to accurately monitor mangroves. In this paper, we present a framework to use drone imagery to calculate correction factors which can improve the accuracy of satellite-based ...
Astrid J. Hsu +5 more
doaj +1 more source

