Results 91 to 100 of about 1,210,874 (307)

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

On Eisenstein series in $M_{2k}(\Gamma_0(N))$ and their applications

open access: yes, 2018
Let $k,N \in \mathbb{N}$ with $N$ square-free and $k>1$. We prove an orthogonal relation and use this to compute the Fourier coefficients of the Eisenstein part of any $f(z) \in M_{2k}(\Gamma_0(N))$ in terms of sum of divisors function. In particular, if
Aygin, Zafer Selcuk
core   +1 more source

Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification

open access: yesFEBS Open Bio, EarlyView.
Chronic kidney disease (CKD) patients often suffer from intestinal and/or mineral and bone disorders. Using a rat model, we showed that uremic vascular calcification is associated with gut barrier alterations (decreased gut mucus production and Nlrp6 gene expression, increased gut inflammation), and plasma retention of gut‐origin uremic toxins (indoxyl
Piotr Bartochowski   +13 more
wiley   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

open access: yesFEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna   +4 more
wiley   +1 more source

Eisenstein Series Identities Involving the Borweins' Cubic Theta Functions

open access: yesJournal of Applied Mathematics, 2012
Based on the theories of Ramanujan's elliptic functions and the (p, k)-parametrization of theta functions due to Alaca et al. (2006, 2007, 2006) we derive certain Eisenstein series identities involving the Borweins' cubic theta functions with the help of
Ernest X. W. Xia, Olivia X. M. Yao
doaj   +1 more source

The Binomial Combinatorial Convolution Sums

open access: yesBritish Journal of Mathematics & Computer Science, 2014
In [1] we can find some formulas of binomial combinatorial convolution sums. Starting from these formulas, we obtain various binomial combinatorial convolution sums.
openaire   +2 more sources

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

open access: yesFEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian   +6 more
wiley   +1 more source

Analysis of the regulation of undecaprenyl diphosphate dephosphorylation in Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
BacA, PgpB, and YbjG phosphatases are involved in undecaprenyl phosphate (C55P) synthesis in Escherichia coli. We analyzed the lipid contents and the gene expression in the gene‐disruption strains. Undecaprenyl diphosphate (C55PP) level increased in the bacA, ybjG double‐disruption strain, but C55P levels were similar in all strains.
Tomotaka Jitsukawa   +2 more
wiley   +1 more source

UR‐cycleGAN: Denoising full‐body low‐dose PET images using cycle‐consistent Generative Adversarial Networks

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose This study aims to develop a CycleGAN based denoising model to enhance the quality of low‐dose PET (LDPET) images, making them as close as possible to standard‐dose PET (SDPET) images. Methods Using a Philips Vereos PET/CT system, whole‐body PET images of fluorine‐18 fluorodeoxyglucose (18F‐FDG) were acquired from 37 patients to ...
Yang Liu, ZhiWu Sun, HaoJia Liu
wiley   +1 more source

Ramanujan’s convolution sum twisted by Dirichlet characters

open access: yesInternational Journal of Number Theory, 2019
We find formulas for convolutions of sum of divisor functions twisted by the Dirichlet character [Formula: see text], which are analogous to Ramanujan’s formula for convolution of usual sum of divisor functions. We use the theory of modular forms to prove our results.
Aygin, Zafer Selcuk, Hong, Nankun
openaire   +3 more sources

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