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Estimates for character sums with various convolutions [PDF]
Acta Arithmetica, 2017 17 ...
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On a shifted convolution sum problem
Journal of Number Theory, 2022 It is proved here that for a holomorphic newform of prime level \( p \) and trivial nebentypus, the shifted convolution sum \(\sum_{m=1}^{\infty } \lambda_f(m)\lambda_f(m+pu)F(m/M) \) is \( \ll p^{1/2+ \varepsilon} M^{3/4}\) for \( p^{1+\varepsilon}\ll M\ll p^{3-\varepsilon} \) and ...
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
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Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
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Fast Gaussian Filter Approximations Comparison on SIMD Computing Platforms
Applied SciencesGaussian filtering, being a convolution with a Gaussian kernel, is a widespread technique in image analysis and computer vision applications. It is the traditional approach for noise reduction.
Ekaterina O. Rybakova +2 more
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A Characterization of the Compound Multiparameter Hermite Gamma Distribution via Gauss’s Principle
The Scientific World Journal, 2013 We consider the class of those distributions that satisfy Gauss's principle (the maximum likelihood estimator of the mean is the sample mean) and have a parameter orthogonal to the mean.
Werner Hürlimann
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Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
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Ramanujan’s Tau-Function and Convolution Sums
European Journal of Theoretical and Applied SciencesWe study certain type of convolution sums involving an arbitrary arithmetic function f, which it is applied to Ramanujan’s tau function when f coincides with the sum of divisors function.
R., Sivaraman +2 more
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