Results 61 to 70 of about 51,880 (308)
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Approximation of classes of convolutions of periodic functions by Zygmund sums in integral metrics [PDF]
U.Z. Grabova
openalex +1 more source
The second moment of twisted modular L-functions
We prove an asymptotic formula with a power saving error term for the (pure or mixed) second moment of central values of L-functions of any two (possibly equal) fixed cusp forms f, g twisted by all primitive characters modulo q, valid for all ...
Blomer, Valentin, Milićević, Djordje
core +1 more source
Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji +3 more
wiley +1 more source
Shifted convolution sums for $GL(3)\times GL(2)$
For the shifted convolution sum $$ D_h(X)=\sum_{m=1}^\infty\lambda_1(1,m)\lambda_2(m+h)V(\frac{m}{X}) $$ where $\lambda_1(1,m)$ are the Fourier coefficients of a $SL(3,\mathbb Z)$ Maass form $\pi_1$, and $\lambda_2(m)$ are those of a $SL(2,\mathbb Z ...
Munshi, Ritabrata
core +1 more source
Mitochondrial fatty acid oxidation is stimulated by red light irradiation
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera +4 more
wiley +1 more source
Fast Gaussian Filter Approximations Comparison on SIMD Computing Platforms
Gaussian filtering, being a convolution with a Gaussian kernel, is a widespread technique in image analysis and computer vision applications. It is the traditional approach for noise reduction.
Ekaterina O. Rybakova +2 more
doaj +1 more source
A Characterization of the Compound Multiparameter Hermite Gamma Distribution via Gauss’s Principle
We consider the class of those distributions that satisfy Gauss's principle (the maximum likelihood estimator of the mean is the sample mean) and have a parameter orthogonal to the mean.
Werner Hürlimann
doaj +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source

