Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
FEBS Open Bio, EarlyView.Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source
Comparative Analysis of the Central Nervous System Safety Pharmacology Profiles of Caffeine and Taurine in Male and Female Mice Using a Modified Irwin Test. [PDF]
Prev Nutr Food SciCho SH +5 more
europepmc +1 more source
FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Comparison of methods for estimating the timing of linear enamel hypoplasia formation: Clinical validation against a known systemicevent. [PDF]
J Dent SciYu CH.
europepmc +1 more source
Acid-Base parameters of cerebrospinal fluid in patients with Febrile Convulsion [PDF]
Introduction: Fever and convulsion is the most common neurologic emergency among children which is observed in 2 to 4 percent of children aged between six months up to six years old and half of them occure between the age of one to two years old.
صالح زاده, فرهاد +2 more
core
FEBS Open Bio, EarlyView.The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez +4 more
wiley +1 more source
Pharmacovigilance analysis of central nervous system adverse events associated with sevoflurane and drug interactions: a disproportionality study based on the FDA adverse event reporting system (FAERS) database. [PDF]
Front PharmacolYu H, Wang B.
europepmc +1 more source
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
FEBS Open Bio, EarlyView.Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
Tranexamic Acid-Induced Seizure After Cardiopulmonary Bypass: A Case Report. [PDF]
A A PractOya K, Maki J, Higashi M.
europepmc +1 more source