Results 41 to 50 of about 393,847 (293)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Measuring The Evolutionary Rate Of Cooling Of ZZ Ceti [PDF]

, 2013
We have finally measured the evolutionary rate of cooling of the pulsating hydrogen atmosphere (DA) white dwarf ZZ Ceti (Ross 548), as reflected by the drift rate of the 213.13260694 s period.
Mukadam, Anjum S., Bischoff-Kim, Agnes, Fraser, Oliver, Corsico, A. H., Montgomery, Michael H., Kepler, S. O., Romero, A. D., Winget, D. E., Hermes, J. J., Riecken, T. S., Kronberg, M. E., Winget, K. I., Falcon, Ross E., Chandler, Dean W., Kuehne, J. W., Sullivan, Denis J., Reaves, D., von Hippel, Ted, Mullally, Fergal, Shipman, H., Thompson, Susan E., Silvestri, N. M., Hynes, Robert I.   +22 more
core   +5 more sources

Estimating Cooling and Heating Degree Days for Variable Base Temperature

Korean Journal of Air-Conditioning and Refrigeration Engineering, 2014
Abstract In general, building energy performance is evaluated with a detailed transient building energy simulation program. However, energy evaluation tools with the bin method are still used, because of their simple and easy way to calculatebuilding energy performance, without reducing their precision.
Pyeongchan Ihm, Soon-Sung Jung, Donghyun Seo   +2 more
openaire   +2 more sources

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Short-Term Load Forecasting of Natural Gas with Deep Neural Network Regression [PDF]

, 2018
Deep neural networks are proposed for short-term natural gas load forecasting. Deep learning has proven to be a powerful tool for many classification problems seeing significant use in machine learning fields such as image recognition and speech ...
Brown, Ronald H., Merkel, Gregory, Povinelli, Richard James   +2 more
core   +2 more sources

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Heating and cooling degree-days vs climate change in years 1979-2021. Evidence from the European Union and Norway

Economics and Environment
Energy consumption depends strongly on weather conditions. Thus, to formulate energy-related policy goals, it is crucial to monitor changes related to the heating degree days (HDD) and cooling degree days (CDD) – widely applied indicators of climate ...
Sylwia Pangsy-Kania, Justyna Biegańska, Floros Flouros, Aneta Sokół   +3 more
doaj   +1 more source

Spatio-temporal analysis of cooling degree day requirement in North East of Iran [PDF]

نشریه جغرافیا و برنامه‌ریزی, 2019
Global warming is one of the current and future challenges for humankind which can have an impact on agriculture, transportation, water resources, energy production, architecture, heating and cooling needs of the building, plant phenology, etc.
abdolreza kashki, sayed mohammad hosseini, farahnaz khoramabadi   +2 more
doaj  

Climate Change and Vulnerabilities of the European Energy Balance

Journal of Sustainable Development of Energy, Water and Environment Systems, 2015
Energy consumption induces climate change but at the same time modifications in climate impact energy sector both in term of supply capacity and shifts in energy demands.
Giuliano Buceti
doaj   +1 more source