Results 81 to 90 of about 328,365 (310)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Comparison of cooling effectiveness of turbine vanes with and without film cooling [PDF]

The cooling effectiveness of three film-cooled vanes were compared to the cooling effectiveness of two non-film-cooled vanes. The comparison indicated that, for the vane configurations and test conditions examined, film cooling had an adverse effect near
Gauntner, D. J., Gauntner, J. W., Gladden, H. J., Yeh, F. C.   +3 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Analysis of Modern Numerical Approaches to Film Cooling Simulation on a Flat Surface: Trends, Errors and Correlation Dependencies

Journal of Mechanical Engineering
An analysis of modern numerical methods for film cooling simulation on a flat surface, considering current CFD (Computational Fluid Dynamics) trends during 2019–2025, is presented in the paper. More than 25 recent studies devoted to 3D CFD simulations of
Oleh V. Shevchuk
doaj   +1 more source

Experimental study effect of diameter and number of spray nozzle holes on counterflow cooling tower to improve cooling effectiveness

MATEC Web of Conferences, 2018
The cooling system is an essential part of the production process within the plant. In the cooling system using cooling tower, efficiency can be improved by increasing the effectiveness of cooling through nozzle modification. This study aims to determine
Fahruddin A'rasy, Muslimin Muslimin, Susilo Ginanjar Deni, Akbar Ali   +3 more
doaj   +1 more source

Film cooling on the pressure surface of a turbine vane [PDF]

Film-cooling-air ejection from the pressure surface of a turbine vane was investigated, and experimental data are presented. This investigation was conducted in a four-vane cascade on a J75-size turbine vane that had a double row of staggered holes in ...
Gauntner, J. W., Gladden, H. J.
core   +1 more source

Enhancement of Cooling Effectiveness with Mist Assisted Film Cooling

World Congress on Momentum, Heat and Mass Transfer, 2019
info:eu-repo/semantics ...
Biswal, Pratibha, Jindal, U, Reddy, Sathi Rajesh   +2 more
openaire   +2 more sources

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Influence of premixed swirl-stabilized flame on the cooling performance of an effusion-cooled combustor liner

Case Studies in Thermal Engineering
The impact of premixed swirl-stabilized flame on the cooling performance of an effusion-cooled combustor liner perforated by cylindrical and fan-shaped holes is investigated under varying blowing ratios.
Xiang Lu, Yongbin Ji, Bing Ge, Shusheng Zang   +3 more
doaj   +1 more source

Numerical Investigation on Film Cooling Mechanism with Different Coolant Delivery Configurations

Journal of Applied Fluid Mechanics, 2021
Kidney vortex has significant impact on film cooling effectiveness, and different kinds of film cooling hole geometry and configuration are developed to weaken or eliminate kidney vortex.
Y. T. Jiang, H. F. Deng, X. L. You, H. J. Zhao, G. Q. Yue   +4 more
doaj