Results 61 to 70 of about 74,264 (312)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Natural ventilation and cooling by evaporation in hot-arid climates [PDF]

open access: yes, 1990
In hot climates, outside air is too hot during the day. In hot arid climates, low humidity increases discomfort. For comfort, hot air should be cooled before flowing into dwellings and moisture in the moving air increased.
Aboul Naga, Mohsen M, Aboul Naga, M.M
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Turbine cooling and heat transfer modelling for gas turbine performance simulation [PDF]

open access: yes, 2015
The successful design of cooling systems for gas turbine engines is a key factor to feasibility of new projects, as the trend for increasing turbine entry temperatures implies requirements for more sophisticated cooling methods.
Apostolidis, Asteris
core  

Experimental Investigation on the Effects of DBD Plasma on the Film Cooling Effectiveness of a 30-Degree Slot

open access: yesApplied Sciences, 2017
The effects of dielectric barrier discharge (DBD) plasma on the film cooling effectiveness of a 30-degree slot was experimentally investigated in a low-speed wind tunnel.
Ye Jee Kim   +3 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Fundamentals of scaling of overall cooling effectiveness with temperature ratio

open access: yes, 2023
In this paper we study the relationship between overall cooling effectiveness (or so-called metal effectiveness) and mainstream-to-coolant total temperature ratio (TR), for typical high-pressure nozzle guide vane (HPNGV) cooling systems.
Cartlidge, James, Povey, Thomas
core   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Self-optimizing Control of Cooling Tower for Efficient Operation of Chilled Water Systems

open access: yes, 2012
The chilled-water systems, mainly consisting of electric chillers and cooling towers, are crucial for the ventilating and air conditioning systems in commercial buildings. Energy efficient operation of such systems is thus important for the energy saving
Li, Xiao   +3 more
core  

Experimental study effect of diameter and number of spray nozzle holes on counterflow cooling tower to improve cooling effectiveness

open access: yesMATEC Web of Conferences, 2018
The cooling system is an essential part of the production process within the plant. In the cooling system using cooling tower, efficiency can be improved by increasing the effectiveness of cooling through nozzle modification. This study aims to determine
Fahruddin A'rasy   +3 more
doaj   +1 more source

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