Results 101 to 110 of about 1,180,485 (310)
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Digital potential of the Russian agro-Industrial complex based on the results of technological innovations [PDF]
BIO Web of ConferencesThe article analyzes the current state of innovation activity and the fundamental features of technological development in the agricultural sector of the economy, identifies barriers and prerequisites for the transition to digital transformation, and ...
Moroz Oksana, Medvedsky Dmitriy
doaj +1 more source
The Organization for Economic Cooperation and Development (OECD)
, 2014 The Organization for Economic Cooperation and Development (OECD)The Organization for Economic Cooperation and Development is one of the international bodies set up by the West after World War II. It is responsible for analysing and assessing the..
Technical Centre for Agricultural and Rural Cooperation
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang +10 more
wiley +1 more source
Ricerche di Pedagogia e DidatticaInvestigating parental involvement has come to the focus of education studies in the past decade as research on family engagement has revealed its positive impact on children’s academic achievement.
Zsófia Kocsis +4 more
doaj +1 more source
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Статистика и экономика, 2016 The article deals with types of innovations typical for organizations of consumer cooperation, innovative potential and its components, condition of internal statistical survey, possibility of its improvement.
Lidia P. Nagovicina, Anna A. Aletdinova
doaj +1 more source
Technical cooperation highlights 2018-2019 [PDF]
, 2019 Asia and the Pacific was the first region to develop a regional road map for implementing the 2030 Agenda for Sustainable Development. The objective of the regional road map is to promote the balanced integration of the three dimensions of sustainable ...
UN.ESCAP
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