Results 81 to 90 of about 587,996 (269)

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Uncommon Mechanism of Mangled Lower Limb Trauma: Case Report of Salvaged Leg Post Gear Box Explosion Injury

Clinical Case Reports
Mangled limb injuries, typically caused by high‐energy trauma, present significant challenges in surgical decision‐making, particularly when considering limb salvage versus primary amputation.
Khalifa Al Alawi, Iman Zaher, Asim Al Baraznji, Ali Darwiche, Mohammed Muneer   +4 more
doaj   +1 more source

BUILDING AN EFFECTIVE ECONOMIC RELATIONS OF THE REPUBLIC OF CRIMEA WITH THE REGIONS OF THE RUSSIAN FEDERATION (ON EXAMPLE OF KURSK REGION) [PDF]

Krymskij Naučnyj Vestnik, 2017
This article discusses the current economic cal situation of the Crimean Republic, trends and its development potential, as well as the main problems of further development of the region.
Sergey Klevtsov, Alexandra Tevyashova
doaj  

High-tech agricultural tools as a determinant of dynamic rationalization of business processes in Russian agriculture [PDF]

BIO Web of Conferences
In the current environment of innovative transformations in the Russian Federation, there is a significant expansion of digital technological products, and there is an active digital optimization of business processes in all national economic sectors ...
Moroz Oksana, Medvedsky Dmitriy
doaj   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

An intelligent early warning method for spatio-temporal deep network considering cascading fault effects in distribution networks

Diance yu yibiao
Cascading faults are prone to cause significant risk of instability hazards to the distribution network system due to the dependency between its components, and eventually lead to the complete collapse of the whole network. Considering that early warning
FANG Zhengji, PAN Kaiyan, KONG Mingzhu, LIU Hua, ZHAO Hongrui, LIU Hongda   +5 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Association of income inequality and aggregate health indicators in Japan: analyses of prefecture-level panel data

Scientific Reports
Evidence indicates that income inequality is associated with poor health outcomes. In Japan, while the relationship between income inequality and self-rated health has been explored, the association between income inequality and aggregate health ...
Hitoshi Murakam, Azusa Iwamoto, Ayako Masu, Miho Sodeno, Rei Haruyama, Sumiyo Okawa   +5 more
doaj   +1 more source

Deception as cooperation

Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences, 2019
Data from my 'Deception as Cooperation ...
openaire   +3 more sources