Results 61 to 70 of about 1,550,810 (307)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Educating Higher Education Students for Innovative Economies: What International Data Tell Us
Tuning Journal for Higher Education, 2014 As innovation increasingly fuels economic growth, higher education institutions and systems face the challenge of equipping students with the skills required by innovative economies.
Francesco Avvisati +2 more
doaj +1 more source
The Neuroscientist, 2013 Cooperation is essential for the functioning of human societies. To better understand how cooperation both succeeds and fails, recent research in cognitive neuroscience has begun to explore novel paradigms to examine how cooperative mechanisms may be encoded in the brain.
M. Stallen, A. G. Sanfey
openaire +6 more sources
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Replication strategies and the evolution of cooperation by exploitation
, 2013 Introducing the concept of replication strategies this paper studies the evolution of cooperation in populations of agents whose offspring follow a social strategy that is determined by a parent's replication strategy. Importantly, social and replication
Brede, M., Tudge, Simon
core +2 more sources
QUALITY EVALUATION OF FRESH RUTABAGA [PDF]
Техника и технология пищевых производств, 2017 The diet of a modern man should contain fruits and vegetables as producers of physiologically active substances. However, rutabaga - primordial Russian vegetable - has been unfairly forgotten in the range of this product group.
Glebova S.Y., Golub O.V.
doaj +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
EC-CTA Fisheries Cooperation Bulletin
, 2014 C Nauen, Editor in Chief. EC Fisheries Cooperation Bulletin, DG VIII/D-5 Development Office Commission of the European Communities, 200 rue de la Loi 1049 Brussels ...
Technical Centre for Agricultural and Rural Cooperation
core +1 more source
COMPULSORY COOPERATION AND COINCIDENTAL COOPERATION
Journal of Positive Management, 2011 The aim of the article is to prove that companies cooperate not only because they wish to, but also because they are forced to do it. Moreover, It turns out that sometimes firms cooperate in strategic alliances with partners which were not selected, but appeared coincidentally.
openaire +5 more sources
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source