Results 41 to 50 of about 1,180,485 (310)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Research and Outlook on Global Energy Interconnection [PDF]

open access: yesE3S Web of Conferences, 2020
Currently, the world is confronted with a series of challenges including resource shortage, climate change, environment pollution and energy poverty, which are rooted in the humanity’s deep dependence on and large-scale consumption of fossil energy.
Li Jun   +5 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

A Parallel Structured Adaptive Mesh Refinement Approach for Complex Turbulent Shear Flows

open access: yesJournal of Fluid Science and Technology, 2012
In numerical fluid dynamic simulations, adaptive mesh refinement (AMR) approaches have recently been growing in popularity, particularly when the target flow field includes complex turbulent shear flows such as jets, mixing layers, and shear layers in ...
Yuichi MATSUO   +2 more
doaj   +1 more source

Seasonal Monitoring of Ocean Parameter Over Green Mussel Cultivation area in West Part of Cirebon Seawater

open access: yesIlmu Kelautan, 2023
West part of Cirebon in the past suffered an extraordinary event due to poisonous food found in green mussel. It is necessary to monitor current water quality over this region since this area still used for green mussel cultivation area.
Mochamad Riam Badriana   +7 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Global Cooperation and the Human Factor in International Relations [PDF]

open access: yes, 2015
This book aims to pave the way for a new interdisciplinary approach to global cooperation research. It does so by bringing in disciplines whose insights about human behaviour might provide a crucial yet hitherto neglected foundation for understanding how

core   +2 more sources

Multilateral cooperation in the Post-Soviet space

open access: yes, 2023
openIn the thesis, I am exploring the multilateral and bilateral cooperation between the Post-Soviet countries starting from the collapse until the present day.
YDYRYSOVA, AEMILIA
core  

Culture and Cooperation [PDF]

open access: yesSSRN Electronic Journal, 2010
Does the cultural background influence the success with which genetically unrelated individuals cooperate in social dilemma situations? In this paper, we provide an answer by analysing the data of Herrmann et al . (2008 a
Gächter, Simon   +2 more
openaire   +8 more sources

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